Skip to content
  • Categories
  • Recent
  • Tags
  • Popular
  • Users
  • Groups
Skins
  • Light
  • Cerulean
  • Cosmo
  • Flatly
  • Journal
  • Litera
  • Lumen
  • Lux
  • Materia
  • Minty
  • Morph
  • Pulse
  • Sandstone
  • Simplex
  • Sketchy
  • Spacelab
  • United
  • Yeti
  • Zephyr
  • Dark
  • Cyborg
  • Darkly
  • Quartz
  • Slate
  • Solar
  • Superhero
  • Vapor

  • Default (No Skin)
  • No Skin
Collapse

The New Coffee Room

  1. TNCR
  2. General Discussion
  3. First Doses First strategy

First Doses First strategy

Scheduled Pinned Locked Moved General Discussion
32 Posts 9 Posters 334 Views
  • Oldest to Newest
  • Newest to Oldest
  • Most Votes
Reply
  • Reply as topic
Log in to reply
This topic has been deleted. Only users with topic management privileges can see it.
  • MikM Away
    MikM Away
    Mik
    wrote on last edited by
    #8

    What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

    “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

    L jon-nycJ 2 Replies Last reply
    • MikM Mik

      What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

      L Offline
      L Offline
      Loki
      wrote on last edited by
      #9

      @mik said in First Doses First strategy:

      What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

      It’s a good question and I suspect the UK has thought through this and balanced against predicted deaths. We just need to see it in writing. I think they believe timeliness of second dose isn’t key and that second dose could be another vaccine. They will know in about a month if they are right.

      1 Reply Last reply
      • MikM Mik

        What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

        jon-nycJ Online
        jon-nycJ Online
        jon-nyc
        wrote on last edited by
        #10

        @mik said in First Doses First strategy:

        What is the value of more single doses applied if you cannot assure the second in a timely fashion?

        Quite high, apparently. We had a thread about it. Moderna showed 80-90% efficacy after the first dose.

        So this decision represents the following tradeoff: Double the number of people being vaccinated now, accept the risk that some people will get their second shot late.

        With 3-4k deaths per day, it seems obvious that it will save lives.

        You were warned.

        1 Reply Last reply
        • bachophileB Offline
          bachophileB Offline
          bachophile
          wrote on last edited by bachophile
          #11

          I think the question of one dose is not so much the efficacy but rather how long does it sustain immunity without the booster.

          If it’s a question of say 80% efficacy but it lasts, then fine. But if one shot is not enough for at least half a year immunity then maybe not.

          No data on it and no question that Pfizer or moderna can’t sign off on something without the data.

          Fixed the typos. Sorry

          jon-nycJ 1 Reply Last reply
          • jon-nycJ Online
            jon-nycJ Online
            jon-nyc
            wrote on last edited by
            #12

            We've given our 8MM shots I think, holding another 8MM in reserve.

            16MM shots would have covered everyone in the US 75 and over. THat's most of the deaths.

            You were warned.

            1 Reply Last reply
            • bachophileB bachophile

              I think the question of one dose is not so much the efficacy but rather how long does it sustain immunity without the booster.

              If it’s a question of say 80% efficacy but it lasts, then fine. But if one shot is not enough for at least half a year immunity then maybe not.

              No data on it and no question that Pfizer or moderna can’t sign off on something without the data.

              Fixed the typos. Sorry

              jon-nycJ Online
              jon-nycJ Online
              jon-nyc
              wrote on last edited by
              #13

              @bachophile said in First Doses First strategy:

              I think the question of one dose is not so much the efficacy but rather how long does it sustain immunity without the booster.

              Right, but the FDF strategy isn't 'fuck the second dose', it's just relying on future deliveries to provide it. In practice there'd be a mix of when people got the second shot.

              Of course Moderna and BioNtech can't sign off because the question they'd be asked to consider: "is it ok to add uncertainty as to when the second dose will come" can only be answered in the negative. But the question to society as a whole is to weigh that risk against the benefit of vaccinating twice as fast in the initial months.

              You were warned.

              1 Reply Last reply
              • jon-nycJ Online
                jon-nycJ Online
                jon-nyc
                wrote on last edited by
                #14

                FWIW the UK implementation is allowing up to 12 weeks to get the second dose.

                It would be interesting to see the modeling behind their decision.

                You were warned.

                1 Reply Last reply
                • jon-nycJ Online
                  jon-nycJ Online
                  jon-nyc
                  wrote on last edited by
                  #15

                  On the other hand, if we really wanted to maximize lives saved, we could greatly improve our strategy without resorting to FDF, simply by prioritizing based on who would benefit the most from early vaccines rather than who 'deserves' an early vaccine.

                  You were warned.

                  RichR 1 Reply Last reply
                  • jon-nycJ jon-nyc

                    On the other hand, if we really wanted to maximize lives saved, we could greatly improve our strategy without resorting to FDF, simply by prioritizing based on who would benefit the most from early vaccines rather than who 'deserves' an early vaccine.

                    RichR Offline
                    RichR Offline
                    Rich
                    wrote on last edited by
                    #16

                    @jon-nyc Do you have numbers on roughly how many are getting it based on the "deserves" it designation? I'm not questioning your basic point, just genuinely interested in the numbers.

                    My 18 year old son who works at McDonalds, (on the grill, with approximately 1 other masked person within 6' of him) has been informed he'll be in group 1c for Connecticut. It was initially going to be 1b, but then they got pushed back.

                    1 Reply Last reply
                    • jon-nycJ Online
                      jon-nycJ Online
                      jon-nyc
                      wrote on last edited by
                      #17

                      As a first approximation take 90% of the essential workers being prioritized above senior citizens. We're talking 10s of millions nationwide.

                      You were warned.

                      1 Reply Last reply
                      • jon-nycJ Online
                        jon-nycJ Online
                        jon-nyc
                        wrote on last edited by
                        #18

                        Here is NY announcement the other day:

                        Starting on Monday, New York State will begin scheduling vaccinations for "Phase 1b" groups—the next category of people eligible for the vaccine. This group includes: People aged 75 and up; education workers (pre-K through 12 teachers and education workers, licensed and registered child care providers, and school-bus drivers); first responders (local police, State Police, Sheriff's Office employees, professional and volunteer firefighters); EMS workers (including professional and volunteer paramedics and EMTs); public transit workers (airline and airport employees, passenger railroad employees, subway and mass transit employees, ferry employees, Port Authority employees, and public bus drivers); and public safety workers. About 3.2 million additional New Yorkers will now be eligible.

                        Note that last sentence. Give me 3.2MM vaccines and I could vaccinate everyone in the state over 62. (figuratively). Deaths would all but cease in Feb.

                        THat's without even doubling using a FDF strategy.

                        You were warned.

                        1 Reply Last reply
                        • jon-nycJ Online
                          jon-nycJ Online
                          jon-nyc
                          wrote on last edited by
                          #19

                          Median age in ICU for covid is ~65, median age in hospital is ~62.

                          So vaccinating 62+ cuts hospital utilization in half.

                          You were warned.

                          1 Reply Last reply
                          • MikM Away
                            MikM Away
                            Mik
                            wrote on last edited by
                            #20

                            Still, you are changing strategy based on hope, not data. Bad idea.

                            https://www.nytimes.com/2021/01/01/world/dr-fauci-advises-against-the-british-approach-of-delaying-a-second-dose-of-vaccine.html

                            “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

                            1 Reply Last reply
                            • RichR Offline
                              RichR Offline
                              Rich
                              wrote on last edited by
                              #21

                              Wow. It still makes a certain amount of sense to me to place 'front line' medical staff at or near the front of the line. (even if using the 'deserves it' reasoning) But all of these other categories ahead of those who clearly have the worst outcomes?

                              It'll be interesting to watch the charts on numbers of deaths and how they relate to what strategy each state uses.

                              I wonder what level of accountability there will or won't be for these decisions. I have a guess...

                              1 Reply Last reply
                              • jon-nycJ jon-nyc

                                The UK is already doing this. Seems almost certain to save lives on net.

                                https://amp.cnn.com/cnn/2021/01/08/politics/biden-vaccine-strategy/index.html?__twitter_impression=true

                                L Offline
                                L Offline
                                Loki
                                wrote on last edited by
                                #22

                                I suspect we know exactly how the vaccine behaves and the real issue is convincing the public.

                                We have likely made up risk that really doesn’t exist.

                                1 Reply Last reply
                                • MikM Away
                                  MikM Away
                                  Mik
                                  wrote on last edited by
                                  #23

                                  Show credible data that contradicts Fauci. My suspicion is this is likely the only thing Biden can do differently than Trump and perhaps claim victory.

                                  But what happened to following the experts' advice? Gone like a fart in the wind.

                                  “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

                                  JollyJ kluursK 2 Replies Last reply
                                  • MikM Mik

                                    Show credible data that contradicts Fauci. My suspicion is this is likely the only thing Biden can do differently than Trump and perhaps claim victory.

                                    But what happened to following the experts' advice? Gone like a fart in the wind.

                                    JollyJ Offline
                                    JollyJ Offline
                                    Jolly
                                    wrote on last edited by
                                    #24

                                    @mik said in First Doses First strategy:

                                    Show credible data that contradicts Fauci. My suspicion is this is likely the only thing Biden can do differently than Trump and perhaps claim victory.

                                    But what happened to following the experts' advice? Gone like a fart in the wind.

                                    Yep.

                                    “Cry havoc and let slip the DOGE of war!”

                                    Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

                                    1 Reply Last reply
                                    • MikM Mik

                                      Show credible data that contradicts Fauci. My suspicion is this is likely the only thing Biden can do differently than Trump and perhaps claim victory.

                                      But what happened to following the experts' advice? Gone like a fart in the wind.

                                      kluursK Offline
                                      kluursK Offline
                                      kluurs
                                      wrote on last edited by
                                      #25

                                      @mik Do the time tested strategy of getting other experts.

                                      1 Reply Last reply
                                      • LuFins DadL Offline
                                        LuFins DadL Offline
                                        LuFins Dad
                                        wrote on last edited by
                                        #26

                                        Which approach helps Social Security Solvency?

                                        The Brad

                                        jon-nycJ 1 Reply Last reply
                                        • LuFins DadL LuFins Dad

                                          Which approach helps Social Security Solvency?

                                          jon-nycJ Online
                                          jon-nycJ Online
                                          jon-nyc
                                          wrote on last edited by
                                          #27

                                          @lufins-dad

                                          Live virus injections. Lots of it. Everyone over 50.

                                          You were warned.

                                          1 Reply Last reply
                                          Reply
                                          • Reply as topic
                                          Log in to reply
                                          • Oldest to Newest
                                          • Newest to Oldest
                                          • Most Votes


                                          • Login

                                          • Don't have an account? Register

                                          • Login or register to search.
                                          • First post
                                            Last post
                                          0
                                          • Categories
                                          • Recent
                                          • Tags
                                          • Popular
                                          • Users
                                          • Groups