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The New Coffee Room

  1. TNCR
  2. General Discussion
  3. First Doses First strategy

First Doses First strategy

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  • jon-nycJ Online
    jon-nycJ Online
    jon-nyc
    wrote on last edited by
    #1

    The UK is already doing this. Seems almost certain to save lives on net.

    https://amp.cnn.com/cnn/2021/01/08/politics/biden-vaccine-strategy/index.html?__twitter_impression=true

    Only non-witches get due process.

    • Cotton Mather, Salem Massachusetts, 1692
    L 1 Reply Last reply
    • CopperC Offline
      CopperC Offline
      Copper
      wrote on last edited by
      #2

      If the plan has Mr. Biden's name on it, it is pure genius, the greatest plan ever.

      JollyJ 1 Reply Last reply
      • CopperC Copper

        If the plan has Mr. Biden's name on it, it is pure genius, the greatest plan ever.

        JollyJ Offline
        JollyJ Offline
        Jolly
        wrote on last edited by
        #3

        @copper said in First Doses First strategy:

        If the plan has Mr. Biden's name on it, it is pure genius, the greatest plan ever.

        Is it as good as President Harris' plan?

        “Cry havoc and let slip the DOGE of war!”

        Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

        CopperC 1 Reply Last reply
        • L Offline
          L Offline
          Loki
          wrote on last edited by Loki
          #4

          Fauci is really really against it but suddenly that doesn’t matter anymore. LOL

          jon-nycJ 1 Reply Last reply
          • JollyJ Jolly

            @copper said in First Doses First strategy:

            If the plan has Mr. Biden's name on it, it is pure genius, the greatest plan ever.

            Is it as good as President Harris' plan?

            CopperC Offline
            CopperC Offline
            Copper
            wrote on last edited by
            #5

            @jolly said in First Doses First strategy:

            @copper said in First Doses First strategy:

            If the plan has Mr. Biden's name on it, it is pure genius, the greatest plan ever.

            Is it as good as President Harris' plan?

            Isn't she wonderful?

            1 Reply Last reply
            • L Loki

              Fauci is really really against it but suddenly that doesn’t matter anymore. LOL

              jon-nycJ Online
              jon-nycJ Online
              jon-nyc
              wrote on last edited by
              #6

              @loki said in First Doses First strategy:

              Fauci is really really against it but suddenly that doesn’t matter anymore. LOL

              What do you think about it?

              Only non-witches get due process.

              • Cotton Mather, Salem Massachusetts, 1692
              L 1 Reply Last reply
              • jon-nycJ jon-nyc

                @loki said in First Doses First strategy:

                Fauci is really really against it but suddenly that doesn’t matter anymore. LOL

                What do you think about it?

                L Offline
                L Offline
                Loki
                wrote on last edited by
                #7

                @jon-nyc said in First Doses First strategy:

                @loki said in First Doses First strategy:

                Fauci is really really against it but suddenly that doesn’t matter anymore. LOL

                What do you think about it?

                I think it’s a great plan. I totally support it. I also support release of the astra Zeneca vaccine now.

                1 Reply Last reply
                • MikM Offline
                  MikM Offline
                  Mik
                  wrote on last edited by
                  #8

                  What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

                  “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

                  L jon-nycJ 2 Replies Last reply
                  • MikM Mik

                    What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

                    L Offline
                    L Offline
                    Loki
                    wrote on last edited by
                    #9

                    @mik said in First Doses First strategy:

                    What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

                    It’s a good question and I suspect the UK has thought through this and balanced against predicted deaths. We just need to see it in writing. I think they believe timeliness of second dose isn’t key and that second dose could be another vaccine. They will know in about a month if they are right.

                    1 Reply Last reply
                    • MikM Mik

                      What is the value of more single doses applied if you cannot assure the second in a timely fashion? I think it is unwise until we know production can meet the need.

                      jon-nycJ Online
                      jon-nycJ Online
                      jon-nyc
                      wrote on last edited by
                      #10

                      @mik said in First Doses First strategy:

                      What is the value of more single doses applied if you cannot assure the second in a timely fashion?

                      Quite high, apparently. We had a thread about it. Moderna showed 80-90% efficacy after the first dose.

                      So this decision represents the following tradeoff: Double the number of people being vaccinated now, accept the risk that some people will get their second shot late.

                      With 3-4k deaths per day, it seems obvious that it will save lives.

                      Only non-witches get due process.

                      • Cotton Mather, Salem Massachusetts, 1692
                      1 Reply Last reply
                      • bachophileB Offline
                        bachophileB Offline
                        bachophile
                        wrote on last edited by bachophile
                        #11

                        I think the question of one dose is not so much the efficacy but rather how long does it sustain immunity without the booster.

                        If it’s a question of say 80% efficacy but it lasts, then fine. But if one shot is not enough for at least half a year immunity then maybe not.

                        No data on it and no question that Pfizer or moderna can’t sign off on something without the data.

                        Fixed the typos. Sorry

                        jon-nycJ 1 Reply Last reply
                        • jon-nycJ Online
                          jon-nycJ Online
                          jon-nyc
                          wrote on last edited by
                          #12

                          We've given our 8MM shots I think, holding another 8MM in reserve.

                          16MM shots would have covered everyone in the US 75 and over. THat's most of the deaths.

                          Only non-witches get due process.

                          • Cotton Mather, Salem Massachusetts, 1692
                          1 Reply Last reply
                          • bachophileB bachophile

                            I think the question of one dose is not so much the efficacy but rather how long does it sustain immunity without the booster.

                            If it’s a question of say 80% efficacy but it lasts, then fine. But if one shot is not enough for at least half a year immunity then maybe not.

                            No data on it and no question that Pfizer or moderna can’t sign off on something without the data.

                            Fixed the typos. Sorry

                            jon-nycJ Online
                            jon-nycJ Online
                            jon-nyc
                            wrote on last edited by
                            #13

                            @bachophile said in First Doses First strategy:

                            I think the question of one dose is not so much the efficacy but rather how long does it sustain immunity without the booster.

                            Right, but the FDF strategy isn't 'fuck the second dose', it's just relying on future deliveries to provide it. In practice there'd be a mix of when people got the second shot.

                            Of course Moderna and BioNtech can't sign off because the question they'd be asked to consider: "is it ok to add uncertainty as to when the second dose will come" can only be answered in the negative. But the question to society as a whole is to weigh that risk against the benefit of vaccinating twice as fast in the initial months.

                            Only non-witches get due process.

                            • Cotton Mather, Salem Massachusetts, 1692
                            1 Reply Last reply
                            • jon-nycJ Online
                              jon-nycJ Online
                              jon-nyc
                              wrote on last edited by
                              #14

                              FWIW the UK implementation is allowing up to 12 weeks to get the second dose.

                              It would be interesting to see the modeling behind their decision.

                              Only non-witches get due process.

                              • Cotton Mather, Salem Massachusetts, 1692
                              1 Reply Last reply
                              • jon-nycJ Online
                                jon-nycJ Online
                                jon-nyc
                                wrote on last edited by
                                #15

                                On the other hand, if we really wanted to maximize lives saved, we could greatly improve our strategy without resorting to FDF, simply by prioritizing based on who would benefit the most from early vaccines rather than who 'deserves' an early vaccine.

                                Only non-witches get due process.

                                • Cotton Mather, Salem Massachusetts, 1692
                                RichR 1 Reply Last reply
                                • jon-nycJ jon-nyc

                                  On the other hand, if we really wanted to maximize lives saved, we could greatly improve our strategy without resorting to FDF, simply by prioritizing based on who would benefit the most from early vaccines rather than who 'deserves' an early vaccine.

                                  RichR Offline
                                  RichR Offline
                                  Rich
                                  wrote on last edited by
                                  #16

                                  @jon-nyc Do you have numbers on roughly how many are getting it based on the "deserves" it designation? I'm not questioning your basic point, just genuinely interested in the numbers.

                                  My 18 year old son who works at McDonalds, (on the grill, with approximately 1 other masked person within 6' of him) has been informed he'll be in group 1c for Connecticut. It was initially going to be 1b, but then they got pushed back.

                                  1 Reply Last reply
                                  • jon-nycJ Online
                                    jon-nycJ Online
                                    jon-nyc
                                    wrote on last edited by
                                    #17

                                    As a first approximation take 90% of the essential workers being prioritized above senior citizens. We're talking 10s of millions nationwide.

                                    Only non-witches get due process.

                                    • Cotton Mather, Salem Massachusetts, 1692
                                    1 Reply Last reply
                                    • jon-nycJ Online
                                      jon-nycJ Online
                                      jon-nyc
                                      wrote on last edited by
                                      #18

                                      Here is NY announcement the other day:

                                      Starting on Monday, New York State will begin scheduling vaccinations for "Phase 1b" groups—the next category of people eligible for the vaccine. This group includes: People aged 75 and up; education workers (pre-K through 12 teachers and education workers, licensed and registered child care providers, and school-bus drivers); first responders (local police, State Police, Sheriff's Office employees, professional and volunteer firefighters); EMS workers (including professional and volunteer paramedics and EMTs); public transit workers (airline and airport employees, passenger railroad employees, subway and mass transit employees, ferry employees, Port Authority employees, and public bus drivers); and public safety workers. About 3.2 million additional New Yorkers will now be eligible.

                                      Note that last sentence. Give me 3.2MM vaccines and I could vaccinate everyone in the state over 62. (figuratively). Deaths would all but cease in Feb.

                                      THat's without even doubling using a FDF strategy.

                                      Only non-witches get due process.

                                      • Cotton Mather, Salem Massachusetts, 1692
                                      1 Reply Last reply
                                      • jon-nycJ Online
                                        jon-nycJ Online
                                        jon-nyc
                                        wrote on last edited by
                                        #19

                                        Median age in ICU for covid is ~65, median age in hospital is ~62.

                                        So vaccinating 62+ cuts hospital utilization in half.

                                        Only non-witches get due process.

                                        • Cotton Mather, Salem Massachusetts, 1692
                                        1 Reply Last reply
                                        • MikM Offline
                                          MikM Offline
                                          Mik
                                          wrote on last edited by
                                          #20

                                          Still, you are changing strategy based on hope, not data. Bad idea.

                                          https://www.nytimes.com/2021/01/01/world/dr-fauci-advises-against-the-british-approach-of-delaying-a-second-dose-of-vaccine.html

                                          “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

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