I wouldn't say he's anti-vax, I'd say he no longer trusts what he was told and I'd say that he, along with a helluva lot of other Americans, is weighing very heavily the cost/benefit ratio of a much less effective booster.
One that I predict will become even less effective by 2023/2024.
Wanna take the shot, take it. Take it in consultation with your physician and what works best for you. But lockdowns don't work, mandates for the general public don't work at this stage of the epidemic.
COVID is here to stay. It will continue to infect and kill people over 65. Well, guess what...That's been happening with flu for many years.
At some point, you do what's best for you and you live life. I think that's where DeSantis is and I think that's where a lot of other people are, too.