Hey Jon

jon-nyc

Wow, that sucks. I'm sorry to hear that.

Would it make a difference if you'd increase the volume of a dose? Like, take three shots at once?

Well the response is dose dependent so something like that. The problem is no institution will do that today except as part of a registered clinical trial.

I’ll likely do it my own sneaky way at some point. Keep in mind there’s still hope for a B-cell and T-cell response.

jon-nyc

@klaus hadn’t seen that science piece but it reports on the same Johns Hopkins study

jon-nyc

That piece in science says they saw some improvement after dose 2 and that their data will be out shortly.

Axtremus

Thanks for your excellent explanation, @jon-nyc .
Didn’t realize that the vaccine efficacy data look so grim for transplant survivors on immunosuppressants. Here’s hoping for robust T-cell and B-cell responses for this population.

jon-nyc

6 weeks after shot 2. Sigh.

Mik

Damn. Damn, damn, damn.

So N95 for the foreseeable future?

jon-nyc

By the way, the UK announced they’ll be offering a 3rd shot to over-50s in the fall. That makes me feel more comfortable going “off-label” and securing a 3rd and possibly a 4th shot.

jon-nyc

@mik Just ordered some more.

Mik

Yeah, I would not hesitate to get another shot or two. Especially since it is getting easier to do so.

jon-nyc

Dose 3 scheduled at 10:45. A rite aid in the Bronx.

Axtremus

@jon-nyc, no word on T-cell and B-cell memories yet?
Sorry it looks like this makes you more dependent on others getting vaccinated, on herd immunity.

jon-nyc

@axtremus Give up I shall not.

Have not yet done the check for B and T cell response.

jon-nyc

I’m in the waiting area now. Much more chill than in March at Javits. Lol

Doctor Phibes

Jon, are you getting the same Pfizer shot, or have you considered mixing them up? I heard a discussion on the radio the other day that there's a theory that using different vaccines could increase their effectiveness. For obvious reasons, it's not something that was tested in development.

jon-nyc

Thought about Moderna and discussed it with a few docs. They thought a Pfizer booster would be better.

Doctor Phibes

The theory is that two different vaccines is a bit like showing your immune systems two different profiles of the same face. It made sense to my totally uneducated brain, but those damn doctors probably know better.

jon-nyc

Well, they just thought that, since the Pfizer response is dose dependent, it would be the most straightforward way.

taiwan_girl

@jon-nyc sending positive thoughts (and antibodies) to you!

Jolly

@jon-nyc said in Hey Jon:

6 weeks after shot 2. Sigh.

Decent box, decent test.

Hope the next shot works better for you...

LuFins Dad

The good news is that you can sell the extra Vaccination Card on the black market for good $$!

Seriously, thoughts and prayers are with you!

The New Coffee Room

Hey Jon