From Copper’s article: Since there is no substitute for human blood, demand can be hard to meet. Yes and no! No substitute for blood itself but some of the protein therapies derived from fractionated plasma can be engineered in a lab. Inhibrx is a company starting P2 trials in 1Q23 for a “FC engineered” recombinant Alpha-1 Antitrypsin protein. It’s actually engineered to oxidize less so it will last longer in the bloodstream than human derived AAT. Not sure if this approach is being investigated for other plasma-derived products such as IVIg or clotting factors for hemophiliacs, but I suspect so.

Watch for Tim Ryan if he wins the Senate.

Just read about the OT 2 point conversion. Ballsy.

Glad he cleared up that confusion about whether he was medically addicted. Also glad science has finally given us a cure for cheeto stains.

Sounds like a “Supergirl” type spinoff.

@jon-nyc said in Stacy Abrams says Black men are stupid: If I lived in GA I’d vote Kemp. I would too. People like Abrams don't build. They tear down. More vengeance than leadership.

@bachophile I've had more than one NG tube go submucosal. When I looked in the pharynx, it's not there, but there's something wiggling under the mucosa at the back of the throat... Hate when that happens.

@George-K ugg

That’s not taking it to them… https://www.si.com/extra-mustard/2022/11/05/img-academy-west-toronto-prep-96-0-halftime-game-called-bishop-sycamore That’s taking it to them…

Some more random pics of BKK [image: 1667728263128-img_8427.jpg] I would think if you were going to spend money on a company sign, you would make sure the words are correct. It's hard to see, but even on the side of the shop, it is spelled wrong also. Too a trip today to Bang Nam Phueng, a three sided "island" in the Chao Praya river. Close to BKK, but seems like a long ways away. [image: 1667728390225-img_8422.jpg] Signs of the recent flooding in BKK. Long and heavy rainy season this year. Fortunately, it appears to be over. [image: 1667728446113-img_8433.jpg] [image: 1667728465662-img_8434.jpg] Our lunch restaurant and my friend (not me) showing off our USD $1.50 spiced pork and rice lunch. (Called Kra Pao in Thai) [image: 1667728540211-img_8436.jpg] Bang Nam Phueng - very rural seeming. [image: 1667728579072-img_8439.jpg] Interesting bug. It actually is only about the size of period dot. Guess it was drinking the water on the table. [image: 1667728641252-img_8447-2.jpg] Thought of @Aqua-Letifer and @jon-nyc and other bike riders when I saw this. Like the Romans, they don't have bike lanes, only wheelchair lanes!! 555

Pretty cool!

It broke the rule, so it is out of line. A couple years ago they loosened up some of the rules related to this. It used to be a penalty if you touched the sand at all. Scroll down to page 5 to see the new rule. https://www.usga.org/content/dam/usga/images/rules/rules-modernization/New-Rules/summary-of-main/Summary of Main Changes_2019 Rules of Golf_FINAL.pdf

@Horace said in Washington Post outs DiSantis' hypocrisy: Typical Republican hypocrite. Damn right. Now, Oprah forsaking Dr. Oz for Fetterman is a TOTALLY different thing, because that's politics.

We have the technology [image: 1667686420647-1edbcc24-5845-426a-ba45-f89f3410165d-image.png]

I watched about three Mandalorians and found it dull. But that is pretty much what I thought about all the Star Wars stuff, even the first one.