Gonna be hard to cook.

They had two molecules wash out but with successively better results. They’re probably 2 years away from clinical trials in their 3rd attempt.

It took them probably 10 years to come up with Trikafta for CF. Though they had successful intermediate products.

@catseye3 said in Hey, Jon:

How did you find your house?

For that matter, how did you weather the Cape during the storm?

I haven’t seen it yet though my neighbor says it’s good. Cape was fine, here at least.

Going home tomorrow

@mik said in The most beautiful guitar pick I have ever seen.:

Gorgeous. How’s it feel?

It's wonderful. No slippage at all.

That's nice, the FAA is there to help.

Yeah, but at what cost to both society and their message?

@mik said in Feeding Felix:

Animals have very accurate senses of time.

And very accurate senses of routine.

For our kids the routine is...

George showers and then feeds. When I go to shower, Boris is sitting at the door, waiting for me.

At about 2:30 PM, Boris hops on the chair by my desk, knowing it's time for a brushing and a treat.

At 7:30 PM, Maggie knows that it's time for her nightly treat.

NPR had a video about how dogs tell time by using scent. I imagine cats are similar.

Regarding Felix, I'd not be surprised if he hears the train approaching much earlier than a human could, and...

@axtremus said in Asset Forfeiture:

In the Executive branch, Eric Holder (under Obama) curbed the practice, then Jeff Sessions (under Trump) revived all of it. Now it’s Merrick Garlands’ turn (under Biden) but he has yet to make any move on this. But, really, this should be a matter of constitutional rights and laws, not a matter of discretion in execution. So Congress and the Courts need to fix this.

You are incorrect. I don't like civil forfeiture either, but what you just wrote is pure democrat spin with absolutely no truth to be found in it. Jeff sessions didn't "revive all of it". What he did was clarify it so that innocent people could better avoid it while making it tougher on criminals.

This is why democrats can't be trusted. They're a bunch of liars.

@doctor-phibes said in Biden "Forcefully" defends Afghan withdrawal:

@george-k said in Biden "Forcefully" defends Afghan withdrawal:

Is there a British term for two twats?

I'm not sure. I do know that the term for a large number of twats is a Twitter.

Now that's funny right there, I don't care who you are...

@rainman said in A Day at the Beach:

Yeah, and I wonder if they sat around and talked about stuff like, "who shot Lincoln?"

As they were Dutch, it seems unlikely. Most of their spare time would probably have been spent discussing the quality of the local dikes.

Hey that was before the surgery.

She’s liked your steaks before, right?

Nuke it to glass…

@89th said in Who am I?:

Sorry is that not allowed? Are people supposed to know that answer without searching?

Nah, but it's much more frustrating to not use it.😛

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@lufins-dad said in Why some A10s have shark teeth noses:

So in short, we stole it from the Brits?

Yes and the Brits had earlier stole it from the Germans.

https://www.aircorpsart.com/blog/the-origins-of-shark-mouth-nose-art/

Damn good thing it wasn't aspirin!

The only thing I picked up on there was that this was not the first time he did it? Yikes.