The New Coffee Room

@Wim Nothing wrong with restoring things. They generally look and function better than the non-restored alternative.

Having unlimited money for aesthetic procedures does make a difference.

@jon-nyc said:

Both prednisone and tacrolimus can increase it but that doesn’t seem to have happened in my case.

A natural LDL-C of 40ng/dl at your age basically doesn't exist. The 0.5% percentile at your age and sex is at 62 ng/dl.

@jon-nyc none of your medications is LDL-lowering, maybe as a side effect? Then that's an amazing value.

I have to get my LDL very low now because of my heart condition. I'm hoping to get in the range you are already in with 10mg of rosuvastatin and 10mg of ezetemibe.

Minneapolis?

I don't think contracts are often intentionally ambiguous, but they are usually incomplete. For instance, most contracts don't specify what happens if aliens interfere.

@jon-nyc said:

Second thing - a clause that said, in case of a dispute, we would flip a coin to see what state’s laws would prevail. Either where they’re incorporated or where we are. It specified a US quarter.

A lawyer once explained something important to me about contracts. They are deliberately incomplete. They don't specify what happens under any possible circumstance because that would be way too elaborate or impossible. The point is that it must be sufficiently expensive to go to court for both sides that the likelihood of resolving an unanticipated situation in a mutually agreed way is high.

I think that clause fits to that idea.

@NobodySock said:

What’s funny is that noone has forced you to read any of this. Enjoy your Japanese piano and I promise to enjoy my American one.

Just two sentences! A good start!

Or a "restrict NS to write max. 100 words per post" thing.

We need a "summarize NS Post in two sentences" plugin.

Bring it on! But I'd rather eat that for dinner!

@jon-nyc said:

Damn. Sorry to hear this but I’m confident you’ll do what you need to do to improve it.

Lucky you found out.

What made you get the test?

It's not a standard recommended test over here, but I thought it would be good to test everything that has a reasonable chance of finding serious problems early (and not too many false positives), and the calcification scoring and the coronary angiography were a part of that.

So far it was a pretty good idea. The colonoscopy found a major polyp that had a good chance of becoming a tumor a decade later. Skin cancer screening found some early signs of skin cancer that were removed. And now this test lets me manage the disease before it has become a problem.

@Andrea-B yes. But I'll up the dosage and add ezetemib. I'm still considering whether adding a psck9 inhibitor would be worth the 8000 Euro or so it would cost per year.
My lipid levels all look excellent, and have been for the last three years, but that doesn't undo the damage of decades before that.

As a routine check, I got a heart CT scan.

The result was rather unexpected. The cross is me and it shows the degree of calcification compared to others my age.

Even though I'm now living very healthy, I was overweight for 20 years, so I guess this is a kind of late revenge. Plaque builds up over decades.

Luckily I discovered this before having any symptoms and I have enough time (and discipline) to manage this disease, such as aggressive cholesterol lowering. I already have the right lifestyle, so I don't need to change all that much (as opposed to, say, having to loose 100 lbs).

That was a story worth reading.

Wait, Microsoft is using Claude Code and not their own OpenAI Codex? That's unexpected...

@mark I'll talk about this with my partner.

Piano party at @mark 's place? Tell me more!

Once a dominant male porcupine finds a prospective female mate, he will approach her and spray his urine on her. The chemical reaction that takes place allows the female to be sexually receptive.

Yeah, that's fun. How similar we are to the animals!

From the perspective of my kids, having a FB account is a completely absurd idea.

I deleted my FB account around 5 years ago and never missed it.