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The New Coffee Room

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  3. Mildly interesting

Mildly interesting

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  • M mark
    11 Feb 2023, 19:32

    There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
    alt text

    G Offline
    G Offline
    George K
    wrote on 11 Feb 2023, 20:00 last edited by George K 2 Nov 2023, 20:00
    #860

    @mark said in Mildly interesting:

    There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects

    Tetrodotoxin

    It's not as simple as that. Unlike classic paralytics (curare), TDX is a sodium-channel blocker whose effects are far wider-reaching than simply blocking the interaction of nerve and muscle.

    This actually "paralyzes" the nerve itself.

    It is the same shit as in pufferfish.

    "Now look here, you Baltic gas passer... " - Mik, 6/14/08

    The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

    M 1 Reply Last reply 11 Feb 2023, 20:20
    • G George K
      11 Feb 2023, 20:00

      @mark said in Mildly interesting:

      There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects

      Tetrodotoxin

      It's not as simple as that. Unlike classic paralytics (curare), TDX is a sodium-channel blocker whose effects are far wider-reaching than simply blocking the interaction of nerve and muscle.

      This actually "paralyzes" the nerve itself.

      It is the same shit as in pufferfish.

      M Offline
      M Offline
      mark
      wrote on 11 Feb 2023, 20:20 last edited by
      #861

      @George-K so, you will not be fine if you are vented for 15 hours?

      G 1 Reply Last reply 11 Feb 2023, 21:53
      • M mark
        11 Feb 2023, 20:20

        @George-K so, you will not be fine if you are vented for 15 hours?

        G Offline
        G Offline
        George K
        wrote on 11 Feb 2023, 21:53 last edited by
        #862

        @mark said in Mildly interesting:

        @George-K so, you will not be fine if you are vented for 15 hours?

        Perhaps, perhaps not. It's not as simple as a paralytic (curare-type) drug.

        Curare and drugs that I used act by physically blocking the receptor on the muscle side of the synapse between muscle and nerve. So, if the nerve fires, the muscle doesn't see the neurotransmitter.

        TTX works on the sodium channel, which causes the nerve to fire.

        Screenshot 2023-02-11 at 3.51.43 PM.png

        Note that many of these symptoms are not related to muscular paralysis.

        "Now look here, you Baltic gas passer... " - Mik, 6/14/08

        The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

        1 Reply Last reply
        • J Online
          J Online
          jon-nyc
          wrote on 12 Feb 2023, 11:55 last edited by
          #863

          Only non-witches get due process.

          • Cotton Mather, Salem Massachusetts, 1692
          1 Reply Last reply
          • K Offline
            K Offline
            kluurs
            wrote on 12 Feb 2023, 15:11 last edited by
            #864

            How hard drives work. here

            1 Reply Last reply
            • M Offline
              M Offline
              mark
              wrote on 13 Feb 2023, 17:08 last edited by mark
              #865

              This is a 773 gram polished Chinga meteorite. The quarter-cut specimen was found in Turvinskaya, Russia and has been cut and polished on two sides. The rest of the meteorite retains its natural light brown crust, creating a dramatic contrast.

              More details/photos: http://bit.ly/3E46k3j

              alt text

              1 Reply Last reply
              • M Offline
                M Offline
                mark
                wrote on 13 Feb 2023, 17:40 last edited by
                #866

                S 1 Reply Last reply 13 Feb 2023, 20:19
                • M mark
                  13 Feb 2023, 17:40

                  S Offline
                  S Offline
                  Sweet Meteor
                  wrote on 13 Feb 2023, 20:19 last edited by
                  #867

                  @mark I pwned you hours ago.

                  1 Reply Last reply
                  • J Online
                    J Online
                    jon-nyc
                    wrote on 16 Feb 2023, 02:38 last edited by
                    #868

                    I stumbled upon the Wikipedia entry for Kmart.

                    This is remarkable:

                    At its peak in 1994, Kmart operated 2,486 stores globally, including 2,323 discount stores and Super Kmart Center locations in the United States. As of April 16, 2022, that number was down to nine, including just three in the continental United States.

                    Only non-witches get due process.

                    • Cotton Mather, Salem Massachusetts, 1692
                    M 1 Reply Last reply 16 Feb 2023, 12:54
                    • J jon-nyc
                      16 Feb 2023, 02:38

                      I stumbled upon the Wikipedia entry for Kmart.

                      This is remarkable:

                      At its peak in 1994, Kmart operated 2,486 stores globally, including 2,323 discount stores and Super Kmart Center locations in the United States. As of April 16, 2022, that number was down to nine, including just three in the continental United States.

                      M Offline
                      M Offline
                      mark
                      wrote on 16 Feb 2023, 12:54 last edited by
                      #869

                      @jon-nyc Huh. I thought it was all gone long ago.

                      J 1 Reply Last reply 16 Feb 2023, 13:04
                      • M mark
                        16 Feb 2023, 12:54

                        @jon-nyc Huh. I thought it was all gone long ago.

                        J Online
                        J Online
                        jon-nyc
                        wrote on 16 Feb 2023, 13:04 last edited by
                        #870

                        @mark

                        That’s part of what’s remarkable. Why keep 3 stores around?

                        Only non-witches get due process.

                        • Cotton Mather, Salem Massachusetts, 1692
                        1 Reply Last reply
                        • L Offline
                          L Offline
                          LuFins Dad
                          wrote on 16 Feb 2023, 13:28 last edited by
                          #871

                          @jon-nyc @mark I was doing a little shopping at a Kmart in Herndon, VA as recently as 10 years ago. They replaced it with a Big Lot’s I believe.

                          The experience was much more low rent than Walmart, though they had many of the same goods.

                          The Brad

                          1 Reply Last reply
                          • G Offline
                            G Offline
                            George K
                            wrote on 16 Feb 2023, 13:46 last edited by
                            #872

                            Does that mean he has 3 lives left?

                            328616691_1331916937627418_6515136614483923374_n.png

                            "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                            The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                            L 1 Reply Last reply 16 Feb 2023, 14:00
                            • G George K
                              16 Feb 2023, 13:46

                              Does that mean he has 3 lives left?

                              328616691_1331916937627418_6515136614483923374_n.png

                              L Offline
                              L Offline
                              LuFins Dad
                              wrote on 16 Feb 2023, 14:00 last edited by
                              #873

                              @George-K said in Mildly interesting:

                              Does that mean he has 3 lives left?

                              328616691_1331916937627418_6515136614483923374_n.png

                              I mean, if I was a sailor on a ship, we brought the cat on board, and saw on it’s collar how many ships sank with it on board, I’d be chucking that beast 50 yards over the port gunwale…

                              The Brad

                              1 Reply Last reply
                              • G Offline
                                G Offline
                                George K
                                wrote on 16 Feb 2023, 14:11 last edited by
                                #874

                                Farrier work.

                                "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                                The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                                M 1 Reply Last reply 16 Feb 2023, 14:36
                                • M Offline
                                  M Offline
                                  mark
                                  wrote on 16 Feb 2023, 14:33 last edited by
                                  #875

                                  Can you freeze a hamster solid then bring it back it to life using microwaves?

                                  Link to video

                                  L 1 Reply Last reply 16 Feb 2023, 23:01
                                  • G George K
                                    16 Feb 2023, 14:11

                                    Farrier work.

                                    M Offline
                                    M Offline
                                    mark
                                    wrote on 16 Feb 2023, 14:36 last edited by
                                    #876

                                    @George-K How often is that performed on a horse's hoof? I bet it stinks something awful when they apply the heated shoe.

                                    What happens to wild horses hooves over time?

                                    G 1 Reply Last reply 16 Feb 2023, 14:46
                                    • M mark
                                      16 Feb 2023, 14:36

                                      @George-K How often is that performed on a horse's hoof? I bet it stinks something awful when they apply the heated shoe.

                                      What happens to wild horses hooves over time?

                                      G Offline
                                      G Offline
                                      George K
                                      wrote on 16 Feb 2023, 14:46 last edited by
                                      #877

                                      @mark said in Mildly interesting:

                                      @George-K How often is that performed on a horse's hoof? I bet it stinks something awful when they apply the heated shoe.

                                      We had Simon seen by the farrier about every six weeks. It's another of those horse-owning expenses that add up, as @jodi can verify!

                                      YEs, it stinks like a MoFo - nothing like it in the world, LOL.

                                      What happens to wild horses hooves over time?

                                      Domesticated horses live a very different life. They spend a lot of time in a stall where the ground is soft, or covered with hay. In the wild, the hooves are constantly being worn down by rocky and rough terrain.

                                      Simon had arthritis problems and the farrier suggested that he go barefoot so that the natural "spring" and give of the hoof would be less stressful on his joints. It seemed to make a difference.

                                      Being a farrier is hard, physical work. You have to have a furnace for heating the shoe, an anvil for pounding the shoe into shape to fit that horse's hoof, etc.

                                      Go to about 5:25.

                                      Link to video

                                      And then, there are some horses that can be "less than cooperative."

                                      It's also very much precision work. A poorly-fitting shoe can really make a horse miserable - just like a poorly fitting shoe in a human.

                                      "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                                      The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                                      M 1 Reply Last reply 16 Feb 2023, 15:50
                                      • G George K
                                        16 Feb 2023, 14:46

                                        @mark said in Mildly interesting:

                                        @George-K How often is that performed on a horse's hoof? I bet it stinks something awful when they apply the heated shoe.

                                        We had Simon seen by the farrier about every six weeks. It's another of those horse-owning expenses that add up, as @jodi can verify!

                                        YEs, it stinks like a MoFo - nothing like it in the world, LOL.

                                        What happens to wild horses hooves over time?

                                        Domesticated horses live a very different life. They spend a lot of time in a stall where the ground is soft, or covered with hay. In the wild, the hooves are constantly being worn down by rocky and rough terrain.

                                        Simon had arthritis problems and the farrier suggested that he go barefoot so that the natural "spring" and give of the hoof would be less stressful on his joints. It seemed to make a difference.

                                        Being a farrier is hard, physical work. You have to have a furnace for heating the shoe, an anvil for pounding the shoe into shape to fit that horse's hoof, etc.

                                        Go to about 5:25.

                                        Link to video

                                        And then, there are some horses that can be "less than cooperative."

                                        It's also very much precision work. A poorly-fitting shoe can really make a horse miserable - just like a poorly fitting shoe in a human.

                                        M Offline
                                        M Offline
                                        mark
                                        wrote on 16 Feb 2023, 15:50 last edited by
                                        #878

                                        @George-K what is the cost of new set of shoes every 6 weeks?

                                        G 1 Reply Last reply 16 Feb 2023, 15:58
                                        • M mark
                                          16 Feb 2023, 15:50

                                          @George-K what is the cost of new set of shoes every 6 weeks?

                                          G Offline
                                          G Offline
                                          George K
                                          wrote on 16 Feb 2023, 15:58 last edited by
                                          #879

                                          @mark in 2005, I was paying $110 - $150 depending on what needed to be done.

                                          "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                                          The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                                          M 1 Reply Last reply 16 Feb 2023, 16:09
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