Mildly interesting
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There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
@mark said in Mildly interesting:
There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
It's not as simple as that. Unlike classic paralytics (curare), TDX is a sodium-channel blocker whose effects are far wider-reaching than simply blocking the interaction of nerve and muscle.
This actually "paralyzes" the nerve itself.
It is the same shit as in pufferfish.
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@mark said in Mildly interesting:
There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
It's not as simple as that. Unlike classic paralytics (curare), TDX is a sodium-channel blocker whose effects are far wider-reaching than simply blocking the interaction of nerve and muscle.
This actually "paralyzes" the nerve itself.
It is the same shit as in pufferfish.
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@mark said in Mildly interesting:
@George-K so, you will not be fine if you are vented for 15 hours?
Perhaps, perhaps not. It's not as simple as a paralytic (curare-type) drug.
Curare and drugs that I used act by physically blocking the receptor on the muscle side of the synapse between muscle and nerve. So, if the nerve fires, the muscle doesn't see the neurotransmitter.
TTX works on the sodium channel, which causes the nerve to fire.
Note that many of these symptoms are not related to muscular paralysis.
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This is a 773 gram polished Chinga meteorite. The quarter-cut specimen was found in Turvinskaya, Russia and has been cut and polished on two sides. The rest of the meteorite retains its natural light brown crust, creating a dramatic contrast.
More details/photos: http://bit.ly/3E46k3j
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@mark I pwned you hours ago.
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I stumbled upon the Wikipedia entry for Kmart.
This is remarkable:
At its peak in 1994, Kmart operated 2,486 stores globally, including 2,323 discount stores and Super Kmart Center locations in the United States. As of April 16, 2022, that number was down to nine, including just three in the continental United States.
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I stumbled upon the Wikipedia entry for Kmart.
This is remarkable:
At its peak in 1994, Kmart operated 2,486 stores globally, including 2,323 discount stores and Super Kmart Center locations in the United States. As of April 16, 2022, that number was down to nine, including just three in the continental United States.
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@George-K said in Mildly interesting:
Does that mean he has 3 lives left?
I mean, if I was a sailor on a ship, we brought the cat on board, and saw on it’s collar how many ships sank with it on board, I’d be chucking that beast 50 yards over the port gunwale…
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@George-K How often is that performed on a horse's hoof? I bet it stinks something awful when they apply the heated shoe.
What happens to wild horses hooves over time?
@mark said in Mildly interesting:
@George-K How often is that performed on a horse's hoof? I bet it stinks something awful when they apply the heated shoe.
We had Simon seen by the farrier about every six weeks. It's another of those horse-owning expenses that add up, as @jodi can verify!
YEs, it stinks like a MoFo - nothing like it in the world, LOL.
What happens to wild horses hooves over time?
Domesticated horses live a very different life. They spend a lot of time in a stall where the ground is soft, or covered with hay. In the wild, the hooves are constantly being worn down by rocky and rough terrain.
Simon had arthritis problems and the farrier suggested that he go barefoot so that the natural "spring" and give of the hoof would be less stressful on his joints. It seemed to make a difference.
Being a farrier is hard, physical work. You have to have a furnace for heating the shoe, an anvil for pounding the shoe into shape to fit that horse's hoof, etc.
Go to about 5:25.
Link to videoAnd then, there are some horses that can be "less than cooperative."
It's also very much precision work. A poorly-fitting shoe can really make a horse miserable - just like a poorly fitting shoe in a human.
