Mildly interesting
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wrote on 10 Feb 2023, 18:58 last edited by
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wrote on 11 Feb 2023, 07:08 last edited by
USS Arizona on the East River, New York 1916.
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USS Arizona on the East River, New York 1916.
wrote on 11 Feb 2023, 10:33 last edited by jon-nyc 2 Nov 2023, 10:54Cool. No doubt heading out of the Brooklyn Navy Yard.
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wrote on 11 Feb 2023, 10:54 last edited by
Liszt’s writing desk.
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wrote on 11 Feb 2023, 12:33 last edited by
@jon-nyc I’ve been to Lizst’s home in Budapest.
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@jon-nyc I’ve been to Lizst’s home in Budapest.
wrote on 11 Feb 2023, 12:58 last edited byMe too.
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wrote on 11 Feb 2023, 17:32 last edited by
Hawa Majal in Jaipur. built 1799.
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wrote on 11 Feb 2023, 19:32 last edited by
There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
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There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
wrote on 11 Feb 2023, 20:00 last edited by George K 2 Nov 2023, 20:00@mark said in Mildly interesting:
There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
It's not as simple as that. Unlike classic paralytics (curare), TDX is a sodium-channel blocker whose effects are far wider-reaching than simply blocking the interaction of nerve and muscle.
This actually "paralyzes" the nerve itself.
It is the same shit as in pufferfish.
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@mark said in Mildly interesting:
There is no antidote for a blue-ringed octopus bite. However, if you can get a ventilator to breathe for you for 15 hours, you survive with no side effects
It's not as simple as that. Unlike classic paralytics (curare), TDX is a sodium-channel blocker whose effects are far wider-reaching than simply blocking the interaction of nerve and muscle.
This actually "paralyzes" the nerve itself.
It is the same shit as in pufferfish.
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wrote on 11 Feb 2023, 21:53 last edited by
@mark said in Mildly interesting:
@George-K so, you will not be fine if you are vented for 15 hours?
Perhaps, perhaps not. It's not as simple as a paralytic (curare-type) drug.
Curare and drugs that I used act by physically blocking the receptor on the muscle side of the synapse between muscle and nerve. So, if the nerve fires, the muscle doesn't see the neurotransmitter.
TTX works on the sodium channel, which causes the nerve to fire.
Note that many of these symptoms are not related to muscular paralysis.
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wrote on 12 Feb 2023, 11:55 last edited by
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wrote on 13 Feb 2023, 17:08 last edited by mark
This is a 773 gram polished Chinga meteorite. The quarter-cut specimen was found in Turvinskaya, Russia and has been cut and polished on two sides. The rest of the meteorite retains its natural light brown crust, creating a dramatic contrast.
More details/photos: http://bit.ly/3E46k3j
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wrote on 13 Feb 2023, 17:40 last edited by
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wrote on 13 Feb 2023, 20:19 last edited by
@mark I pwned you hours ago.
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wrote on 16 Feb 2023, 02:38 last edited by
I stumbled upon the Wikipedia entry for Kmart.
This is remarkable:
At its peak in 1994, Kmart operated 2,486 stores globally, including 2,323 discount stores and Super Kmart Center locations in the United States. As of April 16, 2022, that number was down to nine, including just three in the continental United States.
