What psychedelics really do to your brain

mark · 28 Apr 2021, 17:54

@mik said in What psychedelics really do to your brain:

Forr egg me. I think it made it easier to dismiss those things in my own life. Not recommending it, because you are in a very different space than I was at the time.

I was just partying. lol

xenon · wrote on 28 Apr 2021, 17:44

I've been super curious about this - just because of the rave reviews.

I feel very lucky to be in a good headspace these past few years - but doesn't seem like much downside? I dunno.

mark · wrote on 28 Apr 2021, 17:47

Andy and I were tripping at the college dorms one night and he remembered he had a term paper due in the morning.

We spent sometime coming up with this simple phrase, "double wrap everything in heavy duty plastic". Then we just lost it and laughed our assess off for probably a half hour.

What a silly drug. Fun! but silly.

Mik · M mark 28 Apr 2021, 17:43

@mark said in What psychedelics really do to your brain:

@mik said in What psychedelics really do to your brain:

Forr egg me. I think it made it easier to dismiss those things in my own life. Not recommending it, because you are in a very different space than I was at the time.

I was just partying. lol

me too. I didn't notice these things until long after.

Aqua Letifer · M Mik 28 Apr 2021, 16:55

@mik said in What psychedelics really do to your brain:

Not recommending it, because you are in a very different space than I was at the time.

You say that, but then you also say this:

I have always felt people who have done this find it easier to remove themselves from their deliberations on a given topic.

At the risk of being promoted from Captain to Admiral Obvious, I think that I might benefit from something like that.

Mik · 28 Apr 2021, 18:41

I think these things are better for the younger and more innocent. Too much barefooting around in the head is not good for adults. But I suspect a light dose of mushrooms would not hurt you. I'd try that before I went for some mystical experience. I've been pretty far out there hallucinogenically but cannot say I had something like that. I always knew where I was, even if I couldn't see it quite clearly.

mark · M Mik 28 Apr 2021, 18:18

@mik said in What psychedelics really do to your brain:

I think these things are better for the younger and more innocent. Too much barefooting around in the head is not good for adults. But I suspect a light dose of mushrooms would not hurt you. I'd try that before I went for some mystical experience. I've been pretty far out there hallucinogenically but cannot say I had something like that. I always knew where I was, even if I couldn't see it quite clearly.

This.

Even when your head melts into the tile wall as lean your forehead against it, while you're taking a piss at the local bar across the two lane 55 mph road from the drive through theater where you and your buddies are tripping your brains out at a triple feature on a Friday night, and you decide to play frogger because the bathroom in the bar , across the street, is closer than the bathroom at the drive-in, you know where you are.

When the light trails from the streetlights seem to shoot off into infinity. You still know where you are.

Doctor Phibes · wrote on 28 Apr 2021, 18:43

Mik · wrote on 28 Apr 2021, 18:50

That's Gene Simmons when he wanted to be Ozzy Osbourne. Quite appropriate to this discussion.

Doctor Phibes · wrote on 28 Apr 2021, 19:27

That, my American friend, is Neil.

And you two sound just like him, man.

Mik · wrote on 28 Apr 2021, 19:36

Neil?

Doctor Phibes · 28 Apr 2021, 21:21

He's a Young One. Least ways, he was about 40 years ago.

https://en.wikipedia.org/wiki/The_Young_Ones_(TV_series)

jon-nyc · 28 Apr 2021, 20:13

@mik said in What psychedelics really do to your brain:

Better for the young and innocent who kind of live in Disneyland anyway.

Funny the first time I had acid was at Epcot.

mark · wrote on 28 Apr 2021, 20:13

@jon-nyc said in What psychedelics really do to your brain:

@mik said in What psychedelics really do to your brain:

Better for the young and innocent who kind of live in Disneyland anyway.

Funny the first time I had acid was at Epcot.

Horace · wrote on 28 Apr 2021, 21:21

@doctor-phibes said in What psychedelics really do to your brain:

He's a Young One.

Neil Young, then. Makes sense.

Mik · wrote on 28 Apr 2021, 21:29

Can't be him. Pretty sure he was at the Democratic Socialists convention.

George K · wrote on 29 Apr 2021, 19:56

Happy Birthday Albert Hoffman!

https://en.wikipedia.org/wiki/Albert_Hofmann

While researching lysergic acid derivatives, Hofmann first synthesized LSD on 16 November 1938.[8] The main intention of the synthesis was to obtain a respiratory and circulatory stimulant (analeptic) with no effects on the uterus in analogy to nikethamide (which is also a diethylamide) by introducing this functional group to lysergic acid. It was set aside for five years, until 16 April 1943, when Hofmann decided to reexamine it. While re-synthesizing LSD, he accidentally absorbed a small amount of the drug through his fingertips and discovered its powerful effects.[9] He described what he felt as being:

... affected by a remarkable restlessness, combined with a slight dizziness. At home I lay down and sank into a not unpleasant intoxicated[-]like condition, characterized by an extremely stimulated imagination. In a dreamlike state, with eyes closed (I found the daylight to be unpleasantly glaring), I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away.[10]
Three days later, on 19 April 1943, Hofmann intentionally ingested 250 micrograms of LSD. This day is now known as "Bicycle Day", because he began to feel the effects of the drug as he rode home on a bike. This was the first intentional LSD trip.[11]

Hofmann continued to take small doses of LSD throughout much of his life, and always hoped to find a use for it. In his memoir, he emphasized it as a "sacred drug": "I see the true importance of LSD in the possibility of providing material aid to meditation aimed at the mystical experience of a deeper, comprehensive reality."[12]

Hofmann later discovered 4-Acetoxy-DET (4-acetoxy-N,N-diethyltryptamine, also known as ethacetin, ethylacybin, or 4-AcO-DET); a hallucinogenic tryptamine. He first synthesized 4-AcO-DET in 1958 in the Sandoz lab. Hofmann became director of Sandoz's natural products department and continued studying hallucinogenic substances found in Mexican mushrooms and other plants used by aboriginal people there. This led to the synthesis of psilocybin, the active agent of many "magic mushrooms."[14] Hofmann also became interested in the seeds of the Mexican morning glory species Turbina corymbosa, which are called ololiuqui by natives. He was surprised to find the active compound of ololiuhqui, ergine (LSA, lysergic acid amide) to be closely related to LSD.

mark · wrote on 29 Apr 2021, 21:44

I remember that I was sole pioneer of tripping in my peer group in the mid to late 70s.

The first time I took acid, I took a hit of purple micro-dot and tripped all by myself for the next 14 hours or so. I did have some of my friends close by at the start and of course they had to fuck with me, trying to get me to freak out. lol I had to go home eventually and "sleep" lol. No sleep that night. Just a 15 year old kid in his bed alone, experiencing LSD for the first time. It was a magical, mesmerizing, and at times, scary experience. It lasted so long, and prevented me from sleeping even though I was extremely tired. That felt like torture. It was the longest "buzz" and I did wonder if it would ever stop, and more than worried that it wouldn't. But it did, and I woke up the next day with a entirely different outlook on so many things.

After my friends saw that I survived the trip, they all started doing it. We had some wild parties.

The New Coffee Room

What psychedelics really do to your brain