Ivermectin
-
Just listened to Bret Weinstein's podcast again yesterday. A mea culpa was presented about some pro-Ivermectin study that now seems likely to be fraudulent. But no update to his belief in the value of Ivermectin.
wrote on 29 Aug 2021, 14:24 last edited by@horace said in Ivermectin:
A mea culpa was presented about some pro-Ivermectin study that now seems likely to be fraudulent.
I think you're referring to the Egyptian study. I may have linked to it.
A couple of people found that that study was rife with statistical errors, made-up data, and plagiarism.
-
@horace said in Ivermectin:
A mea culpa was presented about some pro-Ivermectin study that now seems likely to be fraudulent.
I think you're referring to the Egyptian study. I may have linked to it.
A couple of people found that that study was rife with statistical errors, made-up data, and plagiarism.
wrote on 29 Aug 2021, 14:28 last edited by@george-k said in Ivermectin:
@horace said in Ivermectin:
A mea culpa was presented about some pro-Ivermectin study that now seems likely to be fraudulent.
I think you're referring to the Egyptian study. I may have linked to it.
A couple of people found that that study was rife with statistical errors, made-up data, and plagiarism.
Sadly no, I'm not referring to that study. This was another one, I think out of Argentina, which focused on the prophylactic effects of the drug, rather than curative effects. When Bret discussed the Egypt study a couple weeks ago, he shrugged it off, and reminded everybody that he's most excited about the prophylactic value of Ivermectin. Now when discussing this Argentina study, he mentioned that it didn't say anything about the curative properties. Sigh.
-
Here's why I hate the media.
Personally, I have no opinion on the effectiveness of ivermectin. This is NOT an endorsement of the drug.
CNN's Headline: Health officials warn people not to take a drug meant for livestock to ward off or treat Covid-19
Mississippi health officials are warning residents not to take an anti-parasitic drug -- in most cases, a formulation purchased at livestock supply centers -- to treat or prevent Covid-19.
The Mississippi State Department of Health issued an alert on Friday that the Mississippi Poison Control Center has received an increasing number of calls from people who have taken the drug known as ivermectin -- and that at least 70% of such calls related to "ingestion of livestock or animal formulations of ivermectin purchased at livestock supply centers."
While there are human uses for the drug, the US Food and Drug Administration has not approved ivermectin to treat or prevent Covid-19 in humans and the drug is not an anti-viral medication.
Ah, "while there are human uses...."
So, IOW, it's not just a livestock drug as the headline screams.
Ivermectin, sold under the brand name Stromectol among others, is a medication that is used to treat parasite infestations. In humans, this includes head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis.
Assholes.
wrote on 30 Aug 2021, 11:19 last edited by@george-k said in Ivermectin:
Here's why I hate the media.
Personally, I have no opinion on the effectiveness of ivermectin. This is NOT an endorsement of the drug.
CNN's Headline: Health officials warn people not to take a drug meant for livestock to ward off or treat Covid-19
Mississippi health officials are warning residents not to take an anti-parasitic drug -- in most cases, a formulation purchased at livestock supply centers -- to treat or prevent Covid-19.
The Mississippi State Department of Health issued an alert on Friday that the Mississippi Poison Control Center has received an increasing number of calls from people who have taken the drug known as ivermectin -- and that at least 70% of such calls related to "ingestion of livestock or animal formulations of ivermectin purchased at livestock supply centers."
While there are human uses for the drug, the US Food and Drug Administration has not approved ivermectin to treat or prevent Covid-19 in humans and the drug is not an anti-viral medication.
Ah, "while there are human uses...."
So, IOW, it's not just a livestock drug as the headline screams.
Ivermectin, sold under the brand name Stromectol among others, is a medication that is used to treat parasite infestations. In humans, this includes head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis.
Assholes.
Again, this is supposed to be a hard news piece:
-
@george-k said in Ivermectin:
Here's why I hate the media.
Personally, I have no opinion on the effectiveness of ivermectin. This is NOT an endorsement of the drug.
CNN's Headline: Health officials warn people not to take a drug meant for livestock to ward off or treat Covid-19
Mississippi health officials are warning residents not to take an anti-parasitic drug -- in most cases, a formulation purchased at livestock supply centers -- to treat or prevent Covid-19.
The Mississippi State Department of Health issued an alert on Friday that the Mississippi Poison Control Center has received an increasing number of calls from people who have taken the drug known as ivermectin -- and that at least 70% of such calls related to "ingestion of livestock or animal formulations of ivermectin purchased at livestock supply centers."
While there are human uses for the drug, the US Food and Drug Administration has not approved ivermectin to treat or prevent Covid-19 in humans and the drug is not an anti-viral medication.
Ah, "while there are human uses...."
So, IOW, it's not just a livestock drug as the headline screams.
Ivermectin, sold under the brand name Stromectol among others, is a medication that is used to treat parasite infestations. In humans, this includes head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis.
Assholes.
Again, this is supposed to be a hard news piece:
wrote on 30 Aug 2021, 11:29 last edited by@jolly said in Ivermectin:
Again, this is supposed to be a hard news piece:
https://www.msn.com/en-us/news/tv/ivermectin-debacle-exposes-hypocrisy-of-anti-vaccine-crowd/vi-AANQRE2CNN's Pamela Brown reports this includes an anti-parasitic medicine for horses and cows.
AND HUMANS, you assholes.
-
wrote on 30 Aug 2021, 11:50 last edited by
And this is CNN.
It's a great hard news story, but they spent more time researching clips of commentators on FOX than they did on actually reporting the news about the drug.
BTW, did y'all know that CNN has two FTE's tasked to monitoring FOX News programming?
-
wrote on 30 Aug 2021, 12:48 last edited by
The issue is it is almost impossible to get the human form of ivermectin so all the anti vaxxers are sharing tips and tricks to get it in animal form. I saw a FB site (reading it was ghoulish) dedicated to such and some podcasts. It’s still a thing even as a few major anti vax ivermectin taking and pumping leaders in Texas and Florida died of Covid this past week.
So I think the emphasis on animal form has some merit in this context.
-
wrote on 30 Aug 2021, 12:56 last edited by
The amount of dosage is all over the internet. The problem is that people do not follow it or that they're totally unfamiliar with how to deliver a paste dose from a syringe.
Ivermectin may not help them, but a normal dose has a very low probability of hurting them.
-
wrote on 30 Aug 2021, 13:30 last edited by
It's getting crazy in the next county over from me.
-
It's getting crazy in the next county over from me.
wrote on 30 Aug 2021, 13:33 last edited by -
The issue is it is almost impossible to get the human form of ivermectin so all the anti vaxxers are sharing tips and tricks to get it in animal form. I saw a FB site (reading it was ghoulish) dedicated to such and some podcasts. It’s still a thing even as a few major anti vax ivermectin taking and pumping leaders in Texas and Florida died of Covid this past week.
So I think the emphasis on animal form has some merit in this context.
wrote on 30 Aug 2021, 13:46 last edited by@loki said in Ivermectin:
The issue is it is almost impossible to get the human form of ivermectin so all the anti vaxxers are sharing tips and tricks to get it in animal form. I saw a FB site (reading it was ghoulish) dedicated to such and some podcasts. It’s still a thing even as a few major anti vax ivermectin taking and pumping leaders in Texas and Florida died of Covid this past week.
So I think the emphasis on animal form has some merit in this context.
@loki I’ve got about human’s dose worth* leftover from Ruler’s last deworming. Bonus with this one is you can get rid of your tapeworms too.
*actually don’t know anything about human dosage/ route of administration for ivermectin, for horses it’s oral, at 91 mcg/lb, and I’ve got 150lbs-worth leftover. It’s a lovely orange color and I have no idea what flavor it is.
-
It's getting crazy in the next county over from me.
wrote on 30 Aug 2021, 21:10 last edited by@mik said in Ivermectin:
It's getting crazy in the next county over from me.
https://www.cincinnati.com/story/news/2021/08/30/ivermectin-lawsuit-butler-county-judge-orders-hospital-treat-covid-19-patient-drug/5647432001/This seems rather unusual. A court of law forces a hospital to administer a drug described, off label, by an outside doctor.
-
wrote on 2 Sept 2021, 23:36 last edited by
The American Medical Association (AMA), American Pharmacists Association (APhA), and American Society of Health-System Pharmacists (ASHP) strongly oppose the ordering, prescribing, or dispensing of ivermectin to prevent or treat COVID-19 outside of a clinical trial.
Ivermectin is approved by the U.S. Food and Drug Administration (FDA) for human use to treat infections caused by internal and external parasites. It is not approved to prevent or treat COVID-19. Ivermectin is also available to treat certain veterinary conditions; medications formulated or intended for use in animals should not be used by humans. We are alarmed by reports that outpatient prescribing for and dispensing of ivermectin have increased 24-fold since before the pandemic and increased exponentially over the past few months. As such, we are calling for an immediate end to the prescribing, dispensing, and use of ivermectin for the prevention and treatment of COVID-19 outside of a clinical trial. In addition, we are urging physicians, pharmacists, and other prescribers—trusted health care professionals in their communities—to warn patients against the use of ivermectin outside of FDA-approved indications and guidance, whether intended for use in humans or animals, as well as purchasing ivermectin from online stores. Veterinary forms of this medication are highly concentrated for large animals and pose a significant toxicity risk for humans.
-
wrote on 3 Sept 2021, 13:15 last edited by
I had no idea:
https://www.nobelprize.org/prizes/medicine/2015/summary/
the 2015 Nobel Prize in Physiology or Medicine
with one half jointly to
William C. Campbell and Satoshi Ōmura
for their discoveries concerning a novel therapy against infections caused by roundworm parasitesand the other half to
Tu Youyou
for her discoveries concerning a novel therapy against MalariaDiseases caused by parasites have plagued humankind for millennia and constitute a major global health problem. In particular, parasitic diseases affect the world’s poorest populations and represent a huge barrier to improving human health and wellbeing. This year’s Nobel Laureates have developed therapies that have revolutionized the treatment of some of the most devastating parasitic diseases.
William C. Campbell and Satoshi Ōmura discovered a new drug, Avermectin, the derivatives of which have radically lowered the incidence of River Blindness and Lymphatic Filariasis, as well as showing efficacy against an expanding number of other parasitic diseases. Tu Youyou discovered Artemisinin, a drug that has significantly reduced the mortality rates for patients suffering from Malaria.
These two discoveries have provided humankind with powerful new means to combat these debilitating diseases that affect hundreds of millions of people annually. The consequences in terms of improved human health and reduced suffering are immeasurable.
William C. Campbell, an expert in parasite biology working in the USA, acquired Ōmura’s Streptomyces cultures and explored their efficacy. Campbell showed that a component from one of the cultures was remarkably efficient against parasites in domestic and farm animals. The bioactive agent was purified and named Avermectin, which was subsequently chemically modified to a more effective compound called Ivermectin. Ivermectin was later tested in humans with parasitic infections and effectively killed parasite larvae (microfilaria) (Figure 3). Collectively, Ōmura and Campbell’s contributions led to the discovery of a new class of drugs with extraordinary efficacy against parasitic diseases.
Not shilling for it as a treatment for COVID, of course, but it's startling how it's been portrayed as a dangerous drug. Its discoverer won a freaking Nobel Prize!
-
wrote on 3 Sept 2021, 13:54 last edited by
Damn good thing it wasn't aspirin!