The New Coffee Room

The plausible mechanism pathway. That would be awesome for us but it’s only for ultra-rare, which has no formal definition but probably would exclude us.

https://www.fda.gov/news-events/press-announcements/fda-launches-framework-accelerating-development-individualized-therapies-ultra-rare-diseases

It seems to be about individualized gene therapies so far (like single patient diseases - ultra rare). Like that kid in Philadelphia Children’s. They have that kid doctors on stage too.

Kennedy on stage.

It’s starting for real now.

My friend who’s there said there was a fire alarm and they evacuated the building and brought everyone back in. “And it was very cold outside FYI”. lol

11 minutes in and it’s still the banner screen and hold music.

I’m watching this online. It’s just starting. I’ll livestream anything interesting.

Ha

My friend said he went to sleep in New Jersey and woke up in Vail.

We’ve had 16” so far with a little less than 2 more coming though it’s supposed to be done at 2pm.

What makes it worse than last time is most of it came overnight. Last time I could shovel every few hours to keep it manageable but this time I’ll be going out with a shovel attacking a foot and a half of snow.

Some photos. Not very clear because my screens have snow stuck on them.

I used that grill Saturday night.

@89th said in Reflections on college visits:

Is that better than warmcock? Asking for a friend

No but at Mik’s age it’s the best he can do.

@xenon said in The Iran Nuclear Program thread:

Trump has spent the last couple of hours making multiple posts how the bombs obliterated everything.... which probably means they didn't... sigh...

Steve Witkoff yesterday: “Iran is probably a week away from having industrial-grade bomb-making material.”

Interesting except I don’t think there’s any meaningful sense in which China is still communist.

Why not Maple Magats?

If there’s one thing you are, it’s satisfied.

The airport at Puerto Vallarta earlier today.

He deleted the tweet.

It looks good.