A lot of it boils down to re-looking at therapies that are being used by doctors out in the field, which may not have had adequate double-blind studies. But many doctors believe the therapies have value, if used appropriately.I
The treatment flow chart from the paper:
![alt text](https://ars.els-cdn.com/content/image/1-s2.0-S0002934320306732-gr1.jpg)