Nitric Oxide Trial Underway

[mark]

Link to video

[George K]

THere's talk of using sildenafil (Viagra) as a pulmonary vasodilator for this.

If, as suspected, the problem is one of diffusion impairment, rather than redistribution of blood flow, I'm skeptical that increasing blood flow will have a significant impact. Hopefully I'm wrong.

[mark]

[George K]

@mark said in Nitric Oxide Trial Underway:

Remember, sildenafil was originally developed as a heart medication, and found to have an...interesting side effect.

[mark]

Yes, I know that. But was wondering about "interesting side effects" in the ICU.

[George K]

@mark said in Nitric Oxide Trial Underway:

Yes, I know that. But was wondering about "interesting side effects" in the ICU.

Well, yeah. However, sildenafil doesn't do anything without sexual arousal. So you have to be "stimulated" to get it to work. Once it does, however...

On a side note, Mrs. George took care of a guy (actor, songwriter who wrote at least one big hit) in the coronary care unit in the late 70s. One night, she glanced over and saw some unusual activity in his bed. He was polishing the bishop's mitre. She told him, "If you ever do that again, I'll kill you."

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