One-Shot Vaccine from J & J
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J&J’s one-shot Covid vaccine is safe and generates promising immune response in early trial
Johnson & Johnson’s one-dose coronavirus vaccine is safe and appears to generate a promising immune response in both young and elderly volunteers, according to trial data published Wednesday in the New England Journal of Medicine.
J&J scientists randomly assigned healthy adults between the ages of 18 and 55 and those 65 and older to receive a high or low dose of its vaccine — called Ad26.COV2.S — or a placebo. Some participants in the 18-to-55 age group were also selected to receive a second dose of the vaccine.
Most of the volunteers produced detectable neutralizing antibodies, which researchers believe play an important role in defending cells against the virus, after 28 days, according to the trial data. By day 57, all volunteers had detectable antibodies, regardless of vaccine dose or age group, and remained stable for at least 71 days in the 18-to-55 age group.
The most common side effects were fever, fatigue, headache, muscle aches and pain at the injection site, according to the trial data. Side effects were less common in the older age group, who received only one dose of the vaccine, as well as those who received a lower dose of the vaccine, according to the data.
The phase one and two clinical trial data shows a single shot of the vaccine “gives sustainable antibodies,” Dr. Paul Stoffels, chief scientific officer at J&J, told CNBC’s Meg Tirrell in an interview. He added it gives the company “confidence” the vaccine will be highly effective against the virus.
The trial tested 805 volunteers. The company is expected to release results from its 45,000-person phase three trial later this month. J&J is using the same technologies it used to develop its Ebola vaccine for its Covid-19 vaccine.
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The bigger news about this vaccine is that it’s a more traditional vaccine and is not mRNA based. That should help with those that are scared about the Pfizer vaccine:
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The bigger news about this vaccine is that it’s a more traditional vaccine and is not mRNA based. That should help with those that are scared about the Pfizer vaccine:
@lufins-dad said in One-Shot Vaccine from J & J:
The bigger news about this vaccine is that it’s a more traditional vaccine and is not mRNA based. That should help with those that are scared about the Pfizer vaccine:
If you are 75 should you be worried about RNA issues?
Also, If the average age of death is 80 it seems like the pros and cons are a no brainer.
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@lufins-dad said in One-Shot Vaccine from J & J:
The bigger news about this vaccine is that it’s a more traditional vaccine and is not mRNA based. That should help with those that are scared about the Pfizer vaccine:
If you are 75 should you be worried about RNA issues?
Also, If the average age of death is 80 it seems like the pros and cons are a no brainer.
@loki said in One-Shot Vaccine from J & J:
@lufins-dad said in One-Shot Vaccine from J & J:
The bigger news about this vaccine is that it’s a more traditional vaccine and is not mRNA based. That should help with those that are scared about the Pfizer vaccine:
If you are 75 should you be worried about RNA issues?
Also, If the average age of death is 80 it seems like the pros and cons are a no brainer.
I'm seeing a lot of people (and yes, a lot of them are over 75) reluctant to get the vaccine because of the mRNA base of the vaccine.
