AstraZenica pauses vaccine trial due to adverse reaction

[jon-nyc]

Damn. Hopefully it will be determined that it is unrelated but worrying all the same.

This is not one of the new mRNA vaccines either.

https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/

[Loki]

Would be important to know how often a pause happens and how often it is related to the drug. Let’s hear it so we know better how to interpret this.

That said, this is not a great sign.

[Jolly]

No vaccine is 100% safe.

[jon-nyc]

A person familiar with the situation, and who spoke on the condition of anonymity, said that the participant had been enrolled in a Phase 2/3 trial based in the United Kingdom. The individual also said that a volunteer in the U.K. trial had been found to have transverse myelitis, an inflammatory syndrome that affects the spinal cord and is often sparked by viral infections. However, the timing of this diagnosis, and whether it was directly linked to AstraZeneca’s vaccine, is unclear.

[jon-nyc]

Apparently adenovirus (which their vaccine is based on) can cause transverse myelitis. Not sure the frequency but you can see why they’re taking it seriously.

[Doctor Phibes]

Let's see what happens to people taking part in the unofficial Russian trial.

[jon-nyc]

AZ held an investor call today. This is their second halt, last person ended up being diagnosed with MS so they didn’t attribute her adverse event to the vaccine.

https://www.statnews.com/2020/09/09/astrazeneca-covid19-vaccine-trial-hold-patient-report/