I've been asked to take an experimental COVID vaccine
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wrote on 20 Jul 2020, 18:02 last edited by Klaus
One of the companies that is working on a COVID vaccine is in my hometown (Curevac).
I fit into the (rather narrow) criteria of test persons they are seeking.
In total I'd have to show up 12 times; two times to get a vaccine shot and 10 times for checking things. They'd pay me 1300 Euro.
Would you agree?
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wrote on 20 Jul 2020, 18:06 last edited by
Is this going to be one of those vaccines that cause autism?
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wrote on 20 Jul 2020, 18:07 last edited by Loki
What are they testing for? If only safety I wouldn’t bother. If does it work that is a different question.
I would if it increased my odds significantly (Meaning that is the hope) that I wouldn’t get Covid.
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wrote on 20 Jul 2020, 18:10 last edited by Catseye3
Over here the FDA conducts a graduated set of clinical trials, each successive one being larger, and (I think) with each time a more refined product. (Jon would know more. LOTS more.) Is that how it works over there? If so, whereabouts in the program would your trial be?
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wrote on 20 Jul 2020, 18:21 last edited by jon-nyc
I would be open to it. It’s probably a p1 test where they are still testing different doses and you may get a placebo but I would be open to it.
I would have questions about study design and the technology used, but I would at least show up.
Oddly I couldn’t find it here, where I always find clinical trials in the EU. They have several cancer vaccine trials registered.
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wrote on 20 Jul 2020, 18:24 last edited by Horace
I'd do it as a civic duty thing if my participation actually mattered to their ability to get the results they were looking for. But if someone more interested in the money than I would rather have that spot, then I'd gladly let them have it.
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wrote on 20 Jul 2020, 18:25 last edited by
Yep.
The Phase 1 dose escalation trial will assess a dose range of 2µg to 8µg in 168 healthy volunteers aged 18 to 60 years. The objective is to establish the optimal dose while investigating the safety and immune profile of the vaccine candidate.
https://www.clinicaltrialsarena.com/news/curevac-covid-19-vaccine-trial/
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wrote on 20 Jul 2020, 18:27 last edited by jon-nyc
It doesn’t mention placebo but it’s just a press piece. Once it’s registered you can see the relative sizes of each study arm to assess your odds of getting which dose and/or placebo.
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wrote on 20 Jul 2020, 18:33 last edited by jon-nyc
From another piece about Curevac:
In countries where SARS-CoV-2 is less prevalent, such as Germany, trial participants will be less likely to come into contact with the virus; by extension, it will take studies longer to generate efficacy data. The time-pressured nature of COVID-19 vaccine development is leading companies to try to avoid such delays, for example by enrolling healthcare professionals and other groups more likely to be exposed to the coronavirus in efficacy studies.
I wonder if being a family member of a healthcare provider makes you a more attractive candidate (I obviously meant that only figuratively).
Again, once it’s registered, you will see inclusion and exclusion criteria spelled out.
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Yep.
The Phase 1 dose escalation trial will assess a dose range of 2µg to 8µg in 168 healthy volunteers aged 18 to 60 years. The objective is to establish the optimal dose while investigating the safety and immune profile of the vaccine candidate.
https://www.clinicaltrialsarena.com/news/curevac-covid-19-vaccine-trial/
wrote on 20 Jul 2020, 19:24 last edited by@jon-nyc said in I've been asked to take an experimental COVID vaccine:
Yep.
The Phase 1 dose escalation trial will assess a dose range of 2µg to 8µg in 168 healthy volunteers aged 18 to 60 years. The objective is to establish the optimal dose while investigating the safety and immune profile of the vaccine candidate.
https://www.clinicaltrialsarena.com/news/curevac-covid-19-vaccine-trial/
Interesting. The criteria mentioned in the email I received are more narrow (41-60 years, BMI restrictions) but otherwise it sounds like the same study.
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I would be open to it. It’s probably a p1 test where they are still testing different doses and you may get a placebo but I would be open to it.
I would have questions about study design and the technology used, but I would at least show up.
Oddly I couldn’t find it here, where I always find clinical trials in the EU. They have several cancer vaccine trials registered.
wrote on 20 Jul 2020, 19:36 last edited by bachophile@jon-nyc said in I've been asked to take an experimental COVID vaccine:
I would be open to it. It’s probably a p1 test where they are still testing different doses and you may get a placebo but I would be open to it.
I would have questions about study design and the technology used, but I would at least show up.
Oddly I couldn’t find it here, where I always find clinical trials in the EU. They have several cancer vaccine trials registered.
scratch that, looks like a rabies vaccine
aha found the right one now
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wrote on 20 Jul 2020, 19:38 last edited by
i would do it...but then again see my other thread and im not sure i need to be such a hero.
i guess im waiting for the moderna or oxford/astrazenica to become available
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wrote on 21 Jul 2020, 12:16 last edited by
Now I received a document with way more information about the study.
If I'd participate, I'd have a 20% chance of being in the placebo group. The other groups get different amounts of the vaccine.
All in all, it sounds rather time-consuming to participate. So many examinations. So much paperwork. I think I'll let this pass.
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wrote on 21 Jul 2020, 13:47 last edited by
I think I am inclined to participate in a vaccine trial for COVID-19, but like Klaus, I would want to weigh whatever information I can get to (1) get a sense of whether I can trust the people running the trial, (2) whether I would feel "safe enough" to take the vaccine, (3) whether I can give them the time they need to conduct the trial properly.