Bautista, yes. Saldana, no.

[Jolly]

Him? He's 54, he's been a body builder (which the role requires) and the body is bound to be going.

Saldana? She's 44, but with her body type and the heavy make-up, she could easily do this role another 10 years.

https://www.msn.com/en-us/movies/news/zoe-saldaña-says-she-wants-another-actor-to-take-over-playing-gamora-after-she-makes-her-final-marvel-appearance-in-guardians-of-the-galaxy-vol-3/ar-AA1an9wg?ocid=msedgdhp&pc=W129&cvid=3573b280ff244258b71bd49209951ea9&ei=7

[Axtremus]

The heavy makeup also means it won’t be that hard to swap the underlying actress.

[Doctor Phibes]

I'd be more concerned about keeping the same actor for Rocket. The average lifespan of a raccoon is only 2-3 years, so even now they're probably going to have to start thinking of a replacement.

[Axtremus]

Worry not, a genetically manipulated raccoon can probably live many years longer.