High fat diet cuts seizures
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This is the kind of thing you'd see on a click-bait type of site.
Nope: Neurology
Epilepsy's Big Fat “Miracle” Scores Again
Tanya J.W. McDonald, MD, PhD, reviewing Manral M et al. Neurology 2023 Jan 4
In adolescents and adults with drug-resistant epilepsy, a modified Atkins diet combined with ongoing standard drug therapy showed reduced seizure frequency and improved quality of life compared with standard drug therapy alone.
Ketogenic diet therapies (KDTs) are high-fat, low-carbohydrate diets that have been used in patients with seizures for more than a century. KDT use in adults is limited by a lack of rigorous evidence from randomized, controlled trials showing improved seizure control. This study addressed whether the addition of a less-restrictive KDT variant, the modified Atkins diet (MAD), to ongoing standard drug therapy (SDT) improves seizure control, quality of life, and behavioral outcomes in adolescents and adults with nonsurgical drug-resistant epilepsy.
Investigators randomized 160 participants (80 adolescents and 80 adults) to either SDT plus MAD (intervention) or SDT with a normal diet (control) and assessed outcomes at 6 months. Fifty-two participants (32.5%) dropped out due to lack of efficacy, nonacceptance of diet, and inability to follow-up; 108 participants (46 MAD, 62 SDT) completed the study. The proportion of participants with >50% seizure reduction from baseline, the primary study outcome, was significantly higher in the intervention group than in controls using intention-to-treat (26.2% vs. 2.5%) and per-protocol analysis (45.7% vs. 3.2%). Participants in the intervention group also showed significant and clinically meaningful improvements in quality-of-life scores and fewer behavioral problems compared with controls. Adverse events were consistent with those reported in other KDT trials and reversible with diet modification.
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What really pisses me off about reading this type of stuff is the incessant rise of the TLA.
"Now look here, you Baltic gas passer... " - Mik, 6/14/08
The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.
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What really pisses me off about reading this type of stuff is the incessant rise of the TLA.
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