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The New Coffee Room

  1. TNCR
  2. General Discussion
  3. "There is a cure"

"There is a cure"

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  • MikM Offline
    MikM Offline
    Mik
    wrote on last edited by
    #2

    Mucking about with the immune system.

    What could go wrong?

    “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

    1 Reply Last reply
    • RainmanR Offline
      RainmanR Offline
      Rainman
      wrote on last edited by
      #3

      And, only $19.95!
      BUT WAIT!!

      MikM 1 Reply Last reply
      • L Offline
        L Offline
        Loki
        wrote on last edited by
        #4

        If it works great! Time will tell.

        1 Reply Last reply
        • RainmanR Rainman

          And, only $19.95!
          BUT WAIT!!

          MikM Offline
          MikM Offline
          Mik
          wrote on last edited by
          #5

          @Rainman said in "There is a cure":

          And, only $19.95!
          BUT WAIT!!

          There's MORE!!

          “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

          1 Reply Last reply
          • CopperC Offline
            CopperC Offline
            Copper
            wrote on last edited by
            #6

            It's too good.

            1 Reply Last reply
            • JollyJ Offline
              JollyJ Offline
              Jolly
              wrote on last edited by
              #7

              Show me.

              “Cry havoc and let slip the DOGE of war!”

              Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

              George KG 1 Reply Last reply
              • JollyJ Jolly

                Show me.

                George KG Offline
                George KG Offline
                George K
                wrote on last edited by
                #8

                @Jolly said in "There is a cure":

                Show me.

                It's an interesting approach.

                I'm gonna get all medical geeky here, so bear with me.

                In the OR, we commonly use drugs that are muscle relaxants - they are not "relaxants" in the colloquial sense, they are paralytics. They work by preventing the muscle from contracting by blocking the receptor on the muscle that responds to the stimulus of the nerve connecting it. The nerve releases a chemical (acetylcholine) and if the receptor is blocked, the muscle won't contract.

                For decades, the way to reverse the relaxant was to prevent the breakdown of the enzyme that breaks down acetylcholine. As acetylcholine accumulates, it displaces the paralytic, and the muscle can resume normal function. We've done that since the 1960s.

                And then, something new came along (this happened just as I retired). A new drug, suggamadex, became available. It has a totally different mechanism of action. This new drug "surrounds," the paralytic. By making the paralytic "bigger," it can't attach to the muscle receptor, rendering it ineffective.

                This is, basically, the theory behind using the synthetic antibody on the SARS-CoV-2 virus. You make it ineffective, and it's excreted.

                Fascinating.

                Like I said, let's see how it ages, but the theory makes sense.

                "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                1 Reply Last reply
                • JollyJ Offline
                  JollyJ Offline
                  Jolly
                  wrote on last edited by
                  #9

                  Ok...Chasing a different rabbit....Ever have a patient with an unknown pseudocholinesterase problem go wonky on you?

                  “Cry havoc and let slip the DOGE of war!”

                  Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

                  George KG 1 Reply Last reply
                  • JollyJ Jolly

                    Ok...Chasing a different rabbit....Ever have a patient with an unknown pseudocholinesterase problem go wonky on you?

                    George KG Offline
                    George KG Offline
                    George K
                    wrote on last edited by
                    #10

                    @Jolly said in "There is a cure":

                    Ok...Chasing a different rabbit....Ever have a patient with an unknown pseudocholinesterase problem go wonky on you?

                    Only once. She spent a long long time in the recovery room PACU.

                    This was in, yeah, I actually remember the case, 1976.

                    If you're interested, I'll post the details. It was a clusterfuck.

                    "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                    The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                    1 Reply Last reply
                    • jon-nycJ Offline
                      jon-nycJ Offline
                      jon-nyc
                      wrote on last edited by
                      #11

                      This company trades on the pink sheets and has one (ever) clinical trial registered, not yet recruiting, for knee arthritis.

                      Only non-witches get due process.

                      • Cotton Mather, Salem Massachusetts, 1692
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