The Oral COVID vaccine
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Oravax Medical, a company focused on developing ways to deliver drugs by mouth, is preparing to begin clinical trials of its oral Covid-19 vaccine in Israel after getting the green light from the review board at Ichilov Hospital, Tel Aviv’s main hospital.
The trials—pending recruitment and final approval from the country’s health ministry in coming weeks—will initially serve as a “proof of concept” for the capsule vaccine, said Nadav Kidron, CEO of Oravax’s parent company Oramed Pharmaceuticals, in an interview with The Jerusalem Post.
The first trial will involve 24 unvaccinated volunteers, each taking one or two pills, and will investigate the vaccine’s safety and indicators of immunity, moving on to larger Phase 3 trials to demonstrate efficacy if successful.
The vaccine should be “much more resistant to Covid-19 variants,” Kidron said, as it trains the immune system against three viral proteins instead of the single protein targeted by Pfizer and Moderna shots.
Oravax is also developing the capsule as a booster for people who have been vaccinated against Covid-19 before, though its plans to test this are unclear . -
@mik said in The Oral COVID vaccine:
I doubt it. It may work fine but I don’t think many are simply resistant to a shot.
Yes, but the logistics of handing out a pill (particularly in third-world countries) are much simpler than organizing proper storage and distribution of an injectable vaccine.
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love oral
