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The New Coffee Room

  1. TNCR
  2. General Discussion
  3. Grass roots ‘lockdown’

Grass roots ‘lockdown’

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  • J Offline
    J Offline
    Jeffrey
    wrote on last edited by
    #15

    The “children don’t give it to adults” theory is based on the observation that children don’t get very sick and don’t have much of a viral load to pass on when they infrequently do. The immune system of the young seems more adaptable to fighting the virus.

    Spanish Flu was the opposite. Older people had some immunity and the young immune systems had to fight it for the first time.

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    • J Offline
      J Offline
      Jeffrey
      wrote on last edited by
      #16

      Different aged people will have different immune systems with different learned abilities. The young will adapt quicker to new viruses the old will be more resistant to viruses that have been encountered before in the population. Humans have been fighting viruses for 2-3 million years.

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      • J Jeffrey

        Dog to human? Not sure that was confirmed. Clearly it can given enough chances jump species, but pet-human transmission does not seem confirmed as a real risk. Either it jumped from a bat to a civet 20-50 years ago and then humans ate the wrong civet, or it went from a bat to a lab and then to a person who didn’t follow lab protocol. So it can jump species, but Rover and Fluffy don’t seem super risky based on current evidence.

        My guess is that the virus spreads incredibly quickly but with low fatality. I believe that close to 20-25% of NYC residents have had the virus (per random antibody testing), but only a fraction of those were “sick” in the ordinary language sense of the word. This is why it overwhelms almost every political and economic system without a plan ahead of time. By the time it hits hospitals it has already spread widely.

        HoraceH Offline
        HoraceH Offline
        Horace
        wrote on last edited by Horace
        #17

        @Jeffrey said in Grass roots ‘lockdown’:

        My guess is that the virus spreads incredibly quickly but with low fatality. I believe that close to 20-25% of NYC residents have had the virus (per random antibody testing), but only a fraction of those were “sick” in the ordinary language sense of the word. This is why it overwhelms almost every political and economic system without a plan ahead of time. By the time it hits hospitals it has already spread widely.

        If those numbers are accurate then the point at which hospitals become overwhelmed would be at or near the peak demand. We were imagining at the start of the outbreak that the system would break at some small fraction of what an unchecked virus progression would require. But at 25% of the population already having had it, you've seen the ballpark of the worst case scenario.

        Education is extremely important.

        1 Reply Last reply
        • L Offline
          L Offline
          Loki
          wrote on last edited by
          #18

          Newsom today went straight to phase 2 and I heard the governor of Colorado today capitulating toward opening as if he was singing que sera sera.

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          • J Jeffrey

            Dog to human? Not sure that was confirmed. Clearly it can given enough chances jump species, but pet-human transmission does not seem confirmed as a real risk. Either it jumped from a bat to a civet 20-50 years ago and then humans ate the wrong civet, or it went from a bat to a lab and then to a person who didn’t follow lab protocol. So it can jump species, but Rover and Fluffy don’t seem super risky based on current evidence.

            My guess is that the virus spreads incredibly quickly but with low fatality. I believe that close to 20-25% of NYC residents have had the virus (per random antibody testing), but only a fraction of those were “sick” in the ordinary language sense of the word. This is why it overwhelms almost every political and economic system without a plan ahead of time. By the time it hits hospitals it has already spread widely.

            jon-nycJ Online
            jon-nycJ Online
            jon-nyc
            wrote on last edited by
            #19

            @Jeffrey said in Grass roots ‘lockdown’:

            My guess is that the virus spreads incredibly quickly but with low fatality.

            What would you consider 'low'?

            Right now NYC has 19k deaths. If you take the recent antibody test as gospel, you've got 21% of the city that has been infected.

            That would be an infection fatality rate of over 1%. (with case fatality rate exceeding 10%)

            And even that would be a lower bound for two reasons - (1) the antibody test likely had selection bias issues, and (2) I base those numbers on the normal population of the city but many people have left.

            Only non-witches get due process.

            • Cotton Mather, Salem Massachusetts, 1692
            1 Reply Last reply
            • J Offline
              J Offline
              Jeffrey
              wrote on last edited by
              #20

              Horace - I am just guessing. Guessing based on information, but just guessing. What we don’t yet know is staggering. Asymptomatic expanding transmission seems to short circuit our mental warning systems. We know to stay away from people who “look” sick.

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              • jon-nycJ Online
                jon-nycJ Online
                jon-nyc
                wrote on last edited by
                #21

                The 'children don't give it to adults' hypothesis strikes me as confusing absence of evidence for evidence of absence. But I haven't much looked into it.

                I thought Sweden's calculation with respect to schools was more on the economic and social benefits of providing child care.

                Only non-witches get due process.

                • Cotton Mather, Salem Massachusetts, 1692
                L 1 Reply Last reply
                • jon-nycJ jon-nyc

                  The 'children don't give it to adults' hypothesis strikes me as confusing absence of evidence for evidence of absence. But I haven't much looked into it.

                  I thought Sweden's calculation with respect to schools was more on the economic and social benefits of providing child care.

                  L Offline
                  L Offline
                  Loki
                  wrote on last edited by
                  #22

                  @jon-nyc said in Grass roots ‘lockdown’:

                  The 'children don't give it to adults' hypothesis strikes me as confusing absence of evidence for evidence of absence. But I haven't much looked into it.

                  I thought Sweden's calculation with respect to schools was more on the economic and social benefits of providing child care.

                  First I heard of the notion.

                  https://www.sciencemag.org/news/2020/05/should-schools-reopen-kids-role-pandemic-still-mystery#

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                  • J Offline
                    J Offline
                    Jeffrey
                    wrote on last edited by
                    #23

                    Jon - Your numbers seem roughly correct. Not sure how many left the city. Exposure death rate seems to be between .5 and 1 percent. Not sure how to factor in nursing home spread.

                    1 Reply Last reply
                    • J Offline
                      J Offline
                      Jeffrey
                      wrote on last edited by
                      #24

                      Loki - Yes, your article mentions that the Dutch are reopening elementary schools based on the theory that children don’t infect adults. Closing schools helps primarily because then parents don’t contact each other at pick up etc. At least that is the theory. We will know in 4-6 weeks.

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                      • HoraceH Offline
                        HoraceH Offline
                        Horace
                        wrote on last edited by
                        #25

                        As numbers go, fatality rates are among the most misleading, considering the population characteristics of the folk in the numerator.

                        Education is extremely important.

                        1 Reply Last reply
                        • J Offline
                          J Offline
                          Jeffrey
                          wrote on last edited by
                          #26

                          Horace - Yes, but people who have it and recover suggest it is like having a triple flu for 3 weeks. There are plenty of reasons not to want to get it, esp. before they know how to treat it, beyond not dying.

                          What if they “reopen the economy” and no one comes?

                          1 Reply Last reply
                          • HoraceH Offline
                            HoraceH Offline
                            Horace
                            wrote on last edited by
                            #27

                            At some point the numbers will tell us we've reached herd immunity. Then people will go out again. Hopefully masks will remain fashionable.

                            Education is extremely important.

                            1 Reply Last reply
                            • J Offline
                              J Offline
                              Jeffrey
                              wrote on last edited by
                              #28

                              Jon - While I said people were more compliant now than a month ago, nearly everyone I know or see takes risks (e. g. elevator usage) that I consider very very risky. I suspect the virus at this point is endemic and persistent and cannot be driven from the human population. Even if the whole US went into 6 month Wuhan level lockdown, the second we had international travel it would come back. I am not sure any lockdown could nuke the virus. It was just to buy us some time.

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                              • J Offline
                                J Offline
                                Jeffrey
                                wrote on last edited by
                                #29

                                Horace - US herd immunity would require about 1 mill US deaths, in the absence of a vaccine or treatment, even if you use low fatality numbers. And we don’t know that exposure gives lifetime immunity - might be only 2-3 years or some other limited time.

                                1 Reply Last reply
                                • jon-nycJ Online
                                  jon-nycJ Online
                                  jon-nyc
                                  wrote on last edited by
                                  #30

                                  The places that successfully nuke the curve keep travel restrictions in place for precisely that reason - not a ban necessarily, but mandatory isolation.

                                  Only non-witches get due process.

                                  • Cotton Mather, Salem Massachusetts, 1692
                                  1 Reply Last reply
                                  • J Offline
                                    J Offline
                                    Jeffrey
                                    wrote on last edited by
                                    #31

                                    Other than New Zealand or Taiwan or other island - where have such travel restrictions worked? The illegal immigration debate is over the fact that millions walk into our country by foot. Whether you think this is good or bad or just what happens, it doesn’t support a “ nuke the curve and ban entrance” strategy for the US.

                                    1 Reply Last reply
                                    • jon-nycJ Online
                                      jon-nycJ Online
                                      jon-nyc
                                      wrote on last edited by jon-nyc
                                      #32

                                      I think we need to wait to see how it does in bigger places. Lots of countries, maybe most, have a version of it now. China for example. Israel implemented it early, but it might as well be an island nation with a single airport. Korea will be more interesting.

                                      Only non-witches get due process.

                                      • Cotton Mather, Salem Massachusetts, 1692
                                      1 Reply Last reply
                                      • jon-nycJ Online
                                        jon-nycJ Online
                                        jon-nyc
                                        wrote on last edited by jon-nyc
                                        #33

                                        Showed up in my twitter feed this morning. Click through and read the thread.

                                        Only non-witches get due process.

                                        • Cotton Mather, Salem Massachusetts, 1692
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