Link?
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"Back in the day" we used to call it senile dementia. And there was, basically only a few types.
We've been chasing the "amyloid deposit" rabbit wrt Alzheimer's for a while.
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"Back in the day" we used to call it senile dementia. And there was, basically only a few types.
We've been chasing the "amyloid deposit" rabbit wrt Alzheimer's for a while.
We've been chasing the "amyloid deposit" r
Yes, this is a very interesting puzzle, most of it goes over my head.
The guys with the big money placed most of it on amyloid research.
But there are people who say this:
Dr. Daniel Alkon, a longtime NIH neuroscientist who started a company to develop an Alzheimer’s treatment, is even more emphatic: “If it weren’t for the near-total dominance of the idea that amyloid is the only appropriate drug target,” he said, “we would be 10 or 15 years ahead of where we are now.”
https://www.statnews.com/2019/06/25/alzheimers-cabal-thwarted-progress-toward-cure/
Then there is this:
The amyloid hypothesis drama
In AD, brain cells are dying. Additionally, a protein fragment called beta amyloid is building up on the exterior of brain cells. Some believe that amyloid buildup is a primary disease mechanism—it’s killing the cells and/or interfering with the transmission of information between cells. But other researchers I’ve spoken with believe amyloid is a byproduct of the disease process with no real consequence of its own.
Other authorities propose that amyloid plaques are actually a natural protective feature for the cells intended to defend against microbes and toxins.
