HDMI vs USB-C

[George K]

My LG monitor has inputs for either signal. Currently using USB-C.

Is there an unknown (to me) advantage to one vs the other?

Other than USB-C allows the monitor to act as a hub for other USB devices...

[Axtremus]

In theory:
Use HDMI for video.
Use USB-C for everything else (data, power delivery, etc.).

That said, a practical way to decide is to simply try both (with your desired resolution and refresh rate) and see which one gives you more pleasing results.