Hey docs...

[LuFins Dad]

So my doc put me on doxycycline. I just noticed that it says not to take with antacids. I take Famotodine pretty regularly, but even though it’s marketed as an antacid, it’s really a histamine blocker. I looked online and saw where Rolaids, Tums, etc... will cause the antibiotic to be less effective, but I can’t find anything about Famotodine. Any idea?

[Mik]

Rolaids and Tums are primarily calcium.

https://www.drugs.com/drug-interactions/doxycycline-with-famotidine-940-0-1066-0.html#:~:text=Interactions between your drugs,Always consult your healthcare provider.

[Catseye3]

Is this in connection with the tick? Have you heard back on what kind of tick it is?

[George K]

What Mik said.

[LuFins Dad]

@George-K so Famotodine should be fine? It’s bad enough that I can’t have beer or whisky for the next 2 weeks. Add stomach issues and it will be a bad time.

[LuFins Dad]

@Catseye3 I’m not really concerned about whether the tick carried Lyme. It was only likely attached for 12 hours at most, and even if it turns out the tick was carrying Lyme and did manage to transfer it, the antibiotic given for the skin infection treats Lyme.

[LuFins Dad]

This Doxycycline is kicking my ass. Ugh...

[Mik]

How so?

[jon-nyc]

Pussy

[Larry]

Where...

[Jolly]

@LuFins-Dad said in Hey docs...:

This Doxycycline is kicking my ass. Ugh...

Take it with food, drink lots of water and make sure you take a probiotic.

[George K]

@Jolly said in Hey docs...:

@LuFins-Dad said in Hey docs...:

This Doxycycline is kicking my ass. Ugh...

Take it with food, drink lots of water and make sure you take a probiotic.

Yup.

[bachophile]

H2 blockers increase gastric pH and reduce the bioavailability of doxycycline because of reduced absorption. Same hold true of PPIs, and also the calcium carbonate or aluminum hydroxide antacids (tums, maalox) which neutralize gastric acid.