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The New Coffee Room

  1. TNCR
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  3. High Risk

High Risk

Scheduled Pinned Locked Moved General Discussion
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  • AxtremusA Offline
    AxtremusA Offline
    Axtremus
    wrote on last edited by
    #4

    @george-k said in High Risk:

    @jolly said in High Risk:

    He felt that treatment with monoclonal antibodies has been a little under-emphasized and can be as effective as vaccination at preventing death and hospitalization.

    Y0u mentioned this earlier.

    The problem is a logistical one. Monoclonal antibodies are not administered as a simple an injection in the deltoid.

    (Almost) any idiot can shoot a vaccine into an arm (and not follow protocol for aspirate before you inject, by the way), whereas the infrastructure and staffing needs for widespread monoclonal antibodies are huge. How many trained IV starters do you need in a hospital? At Northwestern, by noon, back in March, they were doing about a thousand injections. No hospital can ramp up that kind of response.

    Agree with @George-K’s reply above, which cuts against @Jolly’s characterization that the doc was “even-handed” in his approach to COVID-19.

    I also disagree with his claim that the vaccines have been “oversold”. The reports we read, even those in popular press, quite often state that “this vaccine is x% effective against infection,” “that vaccine is y% effective against death and hospitalization.” Those statements quite clearly do not claim “total protection” (x and y are less than 100). These days, more often than not, “total protection” claims show up as straw-man arguments rather than accurate retelling of history.

    JollyJ 1 Reply Last reply
    • taiwan_girlT Offline
      taiwan_girlT Offline
      taiwan_girl
      wrote on last edited by
      #5

      I wonder about #2. I think that the US drugs testing group is the best in the world - a bit conservative but overall, very careful and do an excellent job.

      Most people (and many doctors) do not have the experience with the 1000's of drugs out there, so to give them free chance to use drugs in an unknown fashion could be quite dangerous.

      1 Reply Last reply
      • JollyJ Offline
        JollyJ Offline
        Jolly
        wrote on last edited by
        #6

        Florida has been very successful with monoclonal antibody infusion centers. How good do you have to be to slide a Jelco into a median cubital vein?

        “Cry havoc and let slip the DOGE of war!”

        Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

        AxtremusA 1 Reply Last reply
        • JollyJ Offline
          JollyJ Offline
          Jolly
          wrote on last edited by
          #7

          And here's something else the doc said, something that I hadn't heard...If you look at the literature, people should understand that they are at a higher risk of catching COVID in the first few days after vaccination, and should take proper precautions.

          “Cry havoc and let slip the DOGE of war!”

          Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

          1 Reply Last reply
          • AxtremusA Axtremus

            @george-k said in High Risk:

            @jolly said in High Risk:

            He felt that treatment with monoclonal antibodies has been a little under-emphasized and can be as effective as vaccination at preventing death and hospitalization.

            Y0u mentioned this earlier.

            The problem is a logistical one. Monoclonal antibodies are not administered as a simple an injection in the deltoid.

            (Almost) any idiot can shoot a vaccine into an arm (and not follow protocol for aspirate before you inject, by the way), whereas the infrastructure and staffing needs for widespread monoclonal antibodies are huge. How many trained IV starters do you need in a hospital? At Northwestern, by noon, back in March, they were doing about a thousand injections. No hospital can ramp up that kind of response.

            Agree with @George-K’s reply above, which cuts against @Jolly’s characterization that the doc was “even-handed” in his approach to COVID-19.

            I also disagree with his claim that the vaccines have been “oversold”. The reports we read, even those in popular press, quite often state that “this vaccine is x% effective against infection,” “that vaccine is y% effective against death and hospitalization.” Those statements quite clearly do not claim “total protection” (x and y are less than 100). These days, more often than not, “total protection” claims show up as straw-man arguments rather than accurate retelling of history.

            JollyJ Offline
            JollyJ Offline
            Jolly
            wrote on last edited by
            #8

            @axtremus said in High Risk:

            @george-k said in High Risk:

            @jolly said in High Risk:

            He felt that treatment with monoclonal antibodies has been a little under-emphasized and can be as effective as vaccination at preventing death and hospitalization.

            Y0u mentioned this earlier.

            The problem is a logistical one. Monoclonal antibodies are not administered as a simple an injection in the deltoid.

            (Almost) any idiot can shoot a vaccine into an arm (and not follow protocol for aspirate before you inject, by the way), whereas the infrastructure and staffing needs for widespread monoclonal antibodies are huge. How many trained IV starters do you need in a hospital? At Northwestern, by noon, back in March, they were doing about a thousand injections. No hospital can ramp up that kind of response.

            Agree with @George-K’s reply above, which cuts against @Jolly’s characterization that the doc was “even-handed” in his approach to COVID-19.

            I also disagree with his claim that the vaccines have been “oversold”. The reports we read, even those in popular press, quite often state that “this vaccine is x% effective against infection,” “that vaccine is y% effective against death and hospitalization.” Those statements quite clearly do not claim “total protection” (x and y are less than 100). These days, more often than not, “total protection” claims show up as straw-man arguments rather than accurate retelling of history.

            If you had a brain, you'd be dangerous.

            “Cry havoc and let slip the DOGE of war!”

            Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

            1 Reply Last reply
            • JollyJ Jolly

              Florida has been very successful with monoclonal antibody infusion centers. How good do you have to be to slide a Jelco into a median cubital vein?

              AxtremusA Offline
              AxtremusA Offline
              Axtremus
              wrote on last edited by
              #9

              @jolly said in High Risk:

              Florida has been very successful with monoclonal antibody infusion centers. How good do you have to be to slide a Jelco into a median cubital vein?

              Pharmacy employees in the likes of CVS and Walgreens can administer vaccine shots. Can they slide a Jelco into a median cubical vein to administer monoclonal antibody?

              George KG 1 Reply Last reply
              • JollyJ Offline
                JollyJ Offline
                Jolly
                wrote on last edited by
                #10

                How many RN's live in your state? Phlebotomists? Med-techs? And assorted other medical professionals?

                “Cry havoc and let slip the DOGE of war!”

                Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

                1 Reply Last reply
                • JollyJ Offline
                  JollyJ Offline
                  Jolly
                  wrote on last edited by
                  #11

                  That is, the ones that aren't being fired for not getting vaxxed?

                  “Cry havoc and let slip the DOGE of war!”

                  Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

                  1 Reply Last reply
                  • AxtremusA Axtremus

                    @jolly said in High Risk:

                    Florida has been very successful with monoclonal antibody infusion centers. How good do you have to be to slide a Jelco into a median cubital vein?

                    Pharmacy employees in the likes of CVS and Walgreens can administer vaccine shots. Can they slide a Jelco into a median cubical vein to administer monoclonal antibody?

                    George KG Offline
                    George KG Offline
                    George K
                    wrote on last edited by
                    #12

                    @axtremus said in High Risk:

                    Pharmacy employees in the likes of CVS and Walgreens can administer vaccine shots. Can they slide a Jelco into a median cubical vein to administer monoclonal antibody?

                    You're talking about a vastly greater skillset.

                    Vastly.

                    Starting an IV is nothing like giving an injection.

                    Nothing.

                    The only thing they have in common is that sharp things are being used.

                    I have no idea how long it takes to administer a dose of monoclonal antibody, but rather than taking seconds (as an injection), an infusion is probably more than 10 minutes. Places like pharmacies simply do not have the infrastructure to do this type of thing.

                    It's a great idea, but functionally beyond impractical.

                    "Now look here, you Baltic gas passer... " - Mik, 6/14/08

                    The saying, "Lite is just one damn thing after another," is a gross understatement. The damn things overlap.

                    1 Reply Last reply
                    • MikM Offline
                      MikM Offline
                      Mik
                      wrote on last edited by
                      #13

                      I know one person who had the monoclonal antibodies and I've had experience with infusion centers. I think it is fine for those at high risk, but it is not a panacea due to both supply and process.

                      “I am fond of pigs. Dogs look up to us. Cats look down on us. Pigs treat us as equals.” ~Winston S. Churchill

                      JollyJ 1 Reply Last reply
                      • LuFins DadL Offline
                        LuFins DadL Offline
                        LuFins Dad
                        wrote on last edited by
                        #14

                        I’m glad that the Regeneron treatment is available and effective, I just wonder why people that are against the vaccine are against having this crap pumped into you.

                        The Brad

                        1 Reply Last reply
                        • MikM Mik

                          I know one person who had the monoclonal antibodies and I've had experience with infusion centers. I think it is fine for those at high risk, but it is not a panacea due to both supply and process.

                          JollyJ Offline
                          JollyJ Offline
                          Jolly
                          wrote on last edited by
                          #15

                          @mik said in High Risk:

                          I know one person who had the monoclonal antibodies and I've had experience with infusion centers. I think it is fine for those at high risk, but it is not a panacea due to both supply and process.

                          Then ramp up production and remake the process.

                          No, it's never going to be as easy as giving a shot. OTOH, training is very minimal for people who are familiar with starting IV's or performing phlebotomies. And there are a lot of people out there with that skill level.

                          “Cry havoc and let slip the DOGE of war!”

                          Those who cheered as J-6 American prisoners were locked in solitary for 18 months without trial, now suddenly fight tooth and nail for foreign terrorists’ "due process". — Buck Sexton

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