Booster?
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Their is sooth in what you say but I don’t know how that works in the real world. It’s probably easier to offer to everyone because most people have waning antibody levels. There will be some I presume that can wait longer than 6 months.
We don’t measure titres for childhood vaccines. Everyone gets the same schedule.
@bachophile said in Booster?:
Their is sooth in what you say but I don’t know how that works in the real world. It’s probably easier to offer to everyone because most people have waning antibody levels. There will be some I presume that can wait longer than 6 months.
We don’t measure titres for childhood vaccines. Everyone gets the same schedule.
Schedule guys for q 6 month antibody draws, if they are over 60. If they ping low, refer them to their PCP or other venue for their booster.
With volume, you could probably get the AB test raw cost to less than $10. As good as y'all are with money, technology and the ability to squeeze a deal, probably a good bit less.
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@bachophile thanks! I didn’t read through it. Does it only cover efficacy or does it cover safety as well? That’s about to become the new rallying cry, I’m sure…
@lufins-dad the New England paper only covered protection from infection and severe disease as a primary objective.
Safety has been reported to the CDC in Pfizer’s phase III as being no different from the first two.
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So it seems the FDA says no boosters….yet
My prediction. Wait three or four months and it will be ok’d. In the meantime plenty of useless deaths.
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So it seems the FDA says no boosters….yet
My prediction. Wait three or four months and it will be ok’d. In the meantime plenty of useless deaths.
@bachophile said in Booster?:
So it seems the FDA says no boosters….yet
My prediction. Wait three or four months and it will be ok’d. In the meantime plenty of useless deaths.
Pushing this stuff through fast should be top priority. Somebody needs to light a fire under the FDA. Trump was praised for doing this by the some of same people that now say the vaccine is risky and/or ineffective.
Politics makes us stupid.
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Ok. Semi reasonable. But I still bet it will be ok’d for everyone eventually. Because hospitals will start filling up with only young patients. Often the parents of school age children who will bring it home with them and infect the parents with waning immunity.
Just sayin.
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Ok. Semi reasonable. But I still bet it will be ok’d for everyone eventually. Because hospitals will start filling up with only young patients. Often the parents of school age children who will bring it home with them and infect the parents with waning immunity.
Just sayin.
@bachophile said in Booster?:
Ok. Semi reasonable. But I still bet it will be ok’d for everyone eventually. Because hospitals will start filling up with only young patients. Often the parents of school age children who will bring it home with them and infect the parents with waning immunity.
Just sayin.
Agree, it feels like this is just a stepping stone and that is the way people need to look at it.
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A scientific advisory committee to the Food and Drug Administration on Friday overwhelmingly recommended against approving a booster shot of the Pfizer-BioNTech coronavirus vaccine for people 16 and older.
The committee voted 16 to 2 after holding an intense daylong public discussion on whether booster shots are necessary and if so, for whom. The Biden administration has been hoping the F.D.A. would approve a third shot of the Pfizer vaccine in time to begin rolling out boosters for Pfizer recipients next week.
The vote came after a sharp debate in which many of the panel’s independent experts, including infectious disease doctors and statisticians, challenged whether the data justified a broad rollout of extra shots when the vaccines appear to still offer robust protection against severe Covid-19 disease and hospitalization, at least in the United States.
“It’s unclear that everyone needs to be boosted, other than a subset of the population that clearly would be at high risk for serious disease,” said Dr. Michael G. Kurilla, a committee member and official at the National Institutes of Health.
It was not immediately clear whether a second vote, on whether booster shots should be approved for older people, who are more vulnerable to severe Covid-19, would follow the first.
Jonathan Sterne, a professor of medical statistics and epidemiology in the United Kingdom, said he had analyzed 76 different studies on the vaccines’ real world effectiveness and found that multiple factors can skew the results, including how many unvaccinated people in a study have natural immunity from prior Covid-19 disease. He also warned against drawing conclusions from short-term results from booster shots; data from Israel, for example, shows only that a booster can enhance protection for a few weeks in older adults.
Israeli experts made a different argument, telling the committee that they believed third Pfizer shots helped dampen a fourth wave of transmission as the Delta variant swept the nation this summer. The Israeli government, which has relied almost entirely on the Pfizer vaccine, began offering booster shots in late July, starting with the elderly.
Dr. Sharon Alroy-Preis, Israel’s head of public health services said the summer’s rise in the number of hospitalized patients who had been fully vaccinated with Pfizer’s vaccine was “scary.” She said 60 percent of severely or critically ill patients and 45 percent of those who died during what she called the fourth surge had received two injections of Pfizer’s vaccine.
After offering boosters to the general population, she said, Israel is now averaging about half as many severe or critically ill patients as anticipated. She said boosters not only helped curb the spread of infection, but “actually saved lives.”
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This post is deleted!
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Vaccine experts advising the Food and Drug Administration voted 19 to 0 Thursday to recommend authorization of an extra dose of Moderna Inc.’s Covid-19 shot, a key step in making booster doses available to millions more people.
A vaccine-advisory panel voted in favor of giving a Moderna booster shot at least six months after the second dose, to adults 65 years and older, as well as adults under 65 who are at high risk of severe Covid-19 or serious complications because of their jobs, living conditions or underlying medical conditions.
The panel voted in favor of a booster shot that is half the dosage of the first two doses. The FDA is expected to decide on whether to authorize the booster dose within days.
Moderna said the booster doses can be drawn from the same vials that contain the original two-dose vaccine series, meaning the boosters will be available soon after authorization.
Science!
Members of the FDA’s vaccine-advisory panel supported Moderna’s booster dose even though the evidence for it was from a small study and had mixed results.
“It’s more a gut feeling rather than based on really truly serious data,” said Patrick Moore, a member of the committee and a professor of molecular genetics and biochemistry at the University of Pittsburgh School of Medicine. “The data itself is not strong, but it is certainly going in the direction that is supportive of this vote.”
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No science either.
https://www.nytimes.com/2021/10/25/health/covid-boosters-cdc-fda.html?smid=tw-nytimes&smtyp=cur
Following a series of endorsements over the last month by scientific panels advising federal agencies, tens of millions of Americans are now eligible for booster shots of coronavirus vaccines.
But the recommendations — even those approved unanimously — mask significant dissent and disquiet among those advisers about the need for booster shots in the United States. …
All the advisers felt that they were obligated to make difficult choices, based on sparse research, in the middle of a public health emergency. But some said they felt compelled to vote for the shots because of the way the federal agencies framed the questions that they were asked to consider.
Other committee experts said that they wanted to avoid confusing the public further by dissenting, or that they voted according to their views of the evidence and were simply overruled.
“These are not evidence-based recommendations,” said Dr. Sarah S. Long, a pediatric infectious disease expert at Drexel University College of Medicine in Philadelphia, and a member of the C.D.C.’s Advisory Committee on Immunization Practices.
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No science either.
https://www.nytimes.com/2021/10/25/health/covid-boosters-cdc-fda.html?smid=tw-nytimes&smtyp=cur
Following a series of endorsements over the last month by scientific panels advising federal agencies, tens of millions of Americans are now eligible for booster shots of coronavirus vaccines.
But the recommendations — even those approved unanimously — mask significant dissent and disquiet among those advisers about the need for booster shots in the United States. …
All the advisers felt that they were obligated to make difficult choices, based on sparse research, in the middle of a public health emergency. But some said they felt compelled to vote for the shots because of the way the federal agencies framed the questions that they were asked to consider.
Other committee experts said that they wanted to avoid confusing the public further by dissenting, or that they voted according to their views of the evidence and were simply overruled.
“These are not evidence-based recommendations,” said Dr. Sarah S. Long, a pediatric infectious disease expert at Drexel University College of Medicine in Philadelphia, and a member of the C.D.C.’s Advisory Committee on Immunization Practices.
Other committee experts said that they wanted to avoid confusing the public further by dissenting,
That is very kind of them
I am easily confused
I just received my Moderna Booster a few minutes ago
But I do feel good about it, Mr. Biden went to so much trouble to provide this vaccine to me, the least I can do is have some shot into my arm
