Donors

I mean, think about it…People’s student loan money was used to listen to Aqua for a couple of hours… Maybe we should forgive part of that…

Oh man, I am so glad Luke didn’t go there…

One or Two High-Step Days May Reduce Mortality Risks

Taking 8,000 steps or more for just 1 or 2 days a week was linked to a significant reduction in all-cause and cardiovascular mortality, according to a study of about 3,000 adults.

Previous research has shown lower mortality rates among individuals who walk consistently, especially those who log at least 8,000 steps daily, but the benefit of intense walking just once or twice a week on long-term health outcomes has not been examined, wrote Kosuke Inoue, MD, of Kyoto University, Japan, and colleagues.

In a study published in JAMA Network Open, the researchers reviewed 10-year follow-up data for 3,101 adults aged 20 years and older who were part of the 2005 and 2006 National Health and Nutrition Examination Survey (NHANES).

The participants were asked to wear accelerometers to track their steps for 7 consecutive days. The researchers assessed the dose-response relationship between days of taking 8,000 steps or more (about 4 miles) during 1 week, and the primary outcome of all-cause mortality risk after 10 years. Cardiovascular mortality risk after 10 years was a secondary outcome.

The mean age of the participants was 50.5 years and 51% were women. The breakdown by ethnicity was 51% White, 21% Black, 24% Hispanic, and 4% other races/ethnicities. A total of 632 individuals took 8,000 steps or more 0 days a week, 532 took at least 8,000 steps 1-2 days per week, and 1,937 took at least 8,000 steps 3-7 days a week.

During the 10-year follow-up period, overall all-cause mortality was 14.2% and cardiovascular mortality was 5.3% across all step groups.

In an adjusted analysis, individuals who took at least 8,000 steps 1-2 days a week had a 14.9% lower all-cause mortality risk compared with those who never reached 8,000 daily steps. This difference was similar to the 16.5% reduced mortality risk for those who took at least 8,000 steps 3-7 days a week.

Similarly, compared with the group with no days of at least 8,000 steps, cardiovascular mortality risk was 8.1% lower for those who took 8,000 steps 1-2 days per week and 8.4% lower for those who took at least 8,000 steps 3-7 days per week. The decreased mortality risk plateaued at 3-4 days.

https://www.axios.com/2023/03/29/office-real-estate-is-getting-kind-of-ugly

One of the shoes yet to drop, but about to, I suppose.

During COVID, we all knew offices became very under utilized. But the office real estate market has not imploded in any spectacular fashion supposedly because most office space leases are long term multi-year deals. More and more of these deals are coming up for renewals. Starting to notice the popular press covering it more.

VPNs at risk?

https://reason.com/2023/03/29/could-the-restrict-act-criminalize-the-use-of-vpns/

There also appears to be language that would allow government officials to access your video devices.

@Mik said in Nashville School Shooting - 6 dead, shooter is a woman:

Are there any love crimes?

The more common phrasing is "crime of passion."

@Catseye3 said in Nashville School Shooting - 6 dead, shooter is a woman:

I have never understood the designation of 'hate crime' as a subcategory of crime. By definition, isn't any crime a hostile act against an individual, and therefore hate-ish? What difference does it make if the crime is committed out of irritation?

Same here.

@LuFins-Dad said in Nashville School Shooting - 6 dead, shooter is a woman:

Twits twill tweet

She has resigned.

Active ingredient is Ivermectin.

Game-Changer Nasal Spray: A Universal Shield Against All COVID-19 Variants

Researchers have developed a molecule that is, when administered nasally, extremely effective in preventing the disease caused by all known variants of SARS-CoV-2, the virus that causes COVID-19. The molecule can be a key tool in preparing for future pandemics, as it is aimed at preventing both the transmission and spread of the virus.

In laboratory animal studies, a molecule known as TriSb92, developed by researchers at the University of Helsinki, has been confirmed as affording effective protection against coronavirus infection. The molecule identifies a region in the spike protein of the coronavirus common to all current variants of the virus and inhibits its functioning.

“When administered nasally, the TriSb92 molecule is extremely effective in preventing infection, and experiments carried out in cell cultures indicate that it also encompasses the very latest variants, including XBB, BF7, and BQ.1.1,” explains Postdoctoral Researcher Anna R. Mäkelä from Professor Kalle Saksela’s research group.

Animal models have also demonstrated that, unlike face masks, the molecule can, when sprayed into the nose, prevent infection even after a few hours of exposure.)